Results 61 to 70 of about 26,594,551 (340)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Batak Cultural Change in Ngeri-ngeri Sedap Movie: Robert N Entman Framing Analysis

Soshum: Jurnal Sosial dan Humaniora, 2023
This research aims to reveal the changes in Batak culture in the movie Ngeri-ngeri Sedap. Ngeri-ngeri Sedap is a family-drama film with a Batak ethnic background, conveying the unrest of overseas children who are bound by customs and culture.
Ega Damayanti, Handriyotopo, Aris Setiawan   +2 more
doaj   +1 more source

Framing, risk perception and social health campaigns: A neuroscientific analysis

, 2023
Health authorities have widely used social health campaigns to improve the attitudesand healthy behaviours of the population. During the COVID-19 pandemic, theybecame an essential tool in increasing compliance with health measures, especially among the ...
Susana Fernandez‐Lores, Fernando E. García‐Muiña, Natividad Crespo‐Tejero, Fernández-Hernandez, Ruth, Fernández-Lores, Susana, Crespo-Tejero, Natividad, García-Muiña, Fernando E., Ruth Fernández‐Hernández, Fernández Lores, Susana   +8 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Framing Climate Services: Logics, Actors, and Implications for Policies and Projects

Atmosphere, 2020
This paper explores how climate services are framed in the literature and possible implications for climate services’ policies and projects. By critically exploring the frames around climate services, the wider objective is to encourage more reflexive ...
Marine Lugen
doaj   +1 more source

Dynamics of Networked Framing: Automated Frame Analysis of Government Media and the Public on Weibo With Pandemic Big Data

Journalism & Mass Communication Quarterly, 2022
Networked framing focuses on how the public becomes gatekeepers on social media. To unpack the dynamics of networked framing, we conducted an automated frame analysis to identify the shift of frame structures of government media (N = 12,090) and the ...
Xinyan Zhao, Xiaohui Wang
semanticscholar   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Animation content in frame analysis [PDF]

Telfor Journal, 2016
Animation frame content is analyzed in this paper. The animation found in frame/video content is usually characterized by specific color distribution and texture. The existence of animation within a frame can be described by carefully selected features. We analyzed both fully and partially animated frames.
G. J. Zajić, M. D. Vesić, A. M. Gavrovska, I. S. Reljin   +3 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Thinking the unthinkable: managerialization of work related suicides as a framing process. [PDF]

Managerialism has been studied in many ways, including diffusion of management techniques notably in public sectors, management ideology or the colonization of everyday life by management thought.
Pezé, Stéphan
core   +2 more sources