Results 51 to 60 of about 84,659 (260)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

MEREK RINTISAN DI MATA MEDIA: Analisis Framing Pemberitaan Kompas terhadap Go-Jek dan Grab Bike di Awal Hadir

open access: yesJournal Communication Spectrum, 2015
The phenomenon of online motorcycle is a new phenomenon that first occurred in Indonesia since 2015 that started since the presence of Go-Jek and GrabBike. The media framed Go-Jek and GrabBike differently.
Stella Fellicia Persulessy
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Framing Russia in Vietnam: A comparative Analysis of National Day Media Coverage

open access: yesRUDN Journal of Studies in Literature and Journalism
This article examines Russia’s image in Quan doi nhan dan and Dan tri during the National Day of the Socialist Republic of Vietnam celebrations reveals a multi-layered media landscape, reflecting both the characteristics of a state-oriented media system ...
Van Thieu Nguyen, Thi Thuy Dung Tran
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Analisis Framing Berita Penangkapan Gubernur Riau Annas Maamun di Surat Kabar Riau Pos dan Tribun Pekanbaru

open access: yesJKG (Jurnal Komunikasi Global), 2018
The arrest of Riau Governor, Annas Maamun on September 25th2014 by the Corruption Eradication Commission (KPK) in Jakarta, has attracted the attention of the mass media because of its news value. In addition to his controversial figure with a seven-month
Al Sukri, Chelsy Yesicha
doaj   +2 more sources

Measuring Nuclear Democracy: A Large-Scale Analysis of German Nuclear Energy Discourse

open access: yesHistories
Nuclear energy has been a highly controversial issue in post-war (West) German politics. Previous research has identified discourse on nuclear energy as an important factor in the development of German political culture.
Maximilian Teich   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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