Results 61 to 70 of about 50,111 (198)
Tecnología en MarchaEl objetivo de este artículo es estudiar la perspectiva curricular de la tecnología en los planes de estudio de Enseñanza del Francés de la UNED. A través de un ejercicio reflexivo de elementos como las perspectivas curriculares, particularmente las ...
César Arguedas-Rojas
doaj +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Revista de Lenguas Modernas, 2011 El presente artículo muestra los resultados obtenidos en las producciones escritas de un grupo de aprendices de francés como segunda lengua en la escuela pública Fernando Terán Valls en Costa Rica.
Kuok-Wa Chao Chao
doaj
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Revista de Lenguas Modernas, 2009 El artículo describe las diferencias en cuanto a las distintas realizaciones fonéticas de las vocales medias abiertas del francés (/e/ - /oe/ - /o/), a partir de análisis acústico-comparativo, entre un hablante nativo de esta lengua y un hablante con un ...
David Pérez Retana
doaj
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Análisis de la interlengua de los aprendices costarricenses de dos escuelas públicas
Revista de Lenguas Modernas, 2013 El presente artículo muestra los resultados obtenidos en las producciones orales de un grupo de aprendices de francés como segunda lengua en las escuelas Fernando Terán Valls y República Francesa en Costa Rica.
Kuok-Wa Chao Chao
doaj
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source