Results 41 to 50 of about 94,153 (248)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Lenguaje, 2014 Este artículo presenta la experiencia radial basada en los principios fundamentales de la pedagogía de la acción para dinamizar ambientes próximos a la realidad comunicativa en el medio monolingüe castellano tunjano hacia el mejoramiento de la lectura y ...
Martha Pardo Segura
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
El feminismo materialista francés: aportes epistemológicos y debates contemporáneos
, 2022 El objetivo del presente proyecto es analizar la corriente feminista materialista francesa en el contexto de los debates teóricos entre feminismo y marxismo de la época. A pesar de que se trata de un hecho poco conocido, el feminismo materialista francés
Bolla, Luisina
core
La cuestión vasca en el hispanismo internacional
Historia contemporánea, 2012 Partiendo de un concepto laxo de hispanismo, este artículo analiza las numerosas aportaciones que han hecho autores italianos, franceses, alemanes, británicos, norteamericanos y de otros países al estudio de la cuestión vasca, entendida en sentido amplio,
José Luis de la Granja Sainz +2 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Modificación de vehículo para circuito
, 2012 Francés Belda, D. (2011). Modificación de vehículo para circuito.
Francés Belda, Daniel
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source