Results 71 to 80 of about 5,977,796 (339)
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Architecture et interdisciplinarité. Le cas d’étude des instituts de la complexité
Un certain nombre d’historiens et de sociologues ont interrogé la relation entre socialisation et architecture. Mais rares sont les auteurs ayant réfléchi au lien entre architecture et production des savoirs scientifiques.
Li Vigni Fabrizio
doaj +1 more source
The education and practice gap of accounting [PDF]
Educators nowadays may equip students for jobs that will not exist in the future (Shusterman, 2015) or jobs that do not exist yet. Many students face confession after graduating from tertiary education.
France, Adrian, Li, Angela
core
Dueling for honor and identity economics [PDF]
Dueling is one of the best indicators of political transition from anarchy to order. This paper explores the dynamics of dueling for honor as a social institution in England, France, and Germany.
Hassani Mahmooei, Behrooz+1 more
core +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Characterization of the first true coaxial 18-fold segmented n-type prototype detector for the GERDA project [PDF]
The first true coaxial 18-fold segmented n-type HPGe prototype detector produced by Canberra-France for the GERDA neutrinoless double beta-decay project was tested both at Canberra-France and at the Max-Planck-Institut fuer Physik in Munich.
A. Caldwell+17 more
core +2 more sources
France is known as a highly centralized country. In fact, the centralist approach applied to the field of urban planning after the Second World War until the end of the twentieth century. However, in 1982 and 1983, a set of decentralization laws changed the situation.
Guelton, Sonia, Verhage, Roelof
openaire +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
History of the french community of historian ...
Veronica Estay Stange, Denis Bertrand
openaire +7 more sources