Results 51 to 60 of about 1,480 (113)

Improving Hip Fracture Prediction by Using Sarcopenia‐Specific Cut‐Offs of T‐Scores for Osteosarcopenia: A Prospective Cohort Study

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Older adults with osteosarcopenia, defined as the coexistence of osteopenia/osteoporosis and sarcopenia, have been associated with an increased risk of fractures compared with those with normal bone mineral density (BMD) and without sarcopenia.
Anjo Zhihui Lu   +7 more
wiley   +1 more source

Systematic screening for age‐related comorbidities: Health care optimization among persons with HIV in an outpatient setting

open access: yesHIV Medicine, Volume 27, Issue 7, Page 1144-1155, July 2026.
Abstract Background Age‐related comorbidities occur earlier and more frequently in people with HIV (PWH) than in the general population and have emerged as a key challenge in long‐term HIV care. Unfortunately, many of these conditions remain undiagnosed, and systematic screening in clinical practice remains limited.
Anna Katrine Haslund Roed   +4 more
wiley   +1 more source

Diabetes and menopause: A critical yet neglected intersection

open access: yes
Diabetic Medicine, EarlyView.
Isabell Haage   +3 more
wiley   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

open access: yesAdvanced Intelligent Discovery, Volume 2, Issue 3, June 2026.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan   +3 more
wiley   +1 more source

Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis

open access: yesArthritis &Rheumatology, Volume 78, Issue 5, Page 1176-1183, May 2026.
Objective Transition from long‐term denosumab (Dmab) to parathyroid hormone‐analogs or romosozumab (Romo) might expose patients to the risk of the so‐called rebound phenomenon. Adding Romo to Dmab might represent an option in patients experiencing a fracture while on Dmab.
Giovanni Adami   +10 more
wiley   +1 more source

Why Osteosarcopenia Matters: Clinical and Investigative Implications

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Osteosarcopenia: Non‐pharmacological and pharmacological treatment strategies. ABSTRACT Background Osteosarcopenia, the combination of osteoporosis and sarcopenia, is a geriatric syndrome linked to functional decline, falls, and fragility fractures. The interaction among bone, muscle, and their shared pathophysiology is driven by mechanical, metabolic,
Erik Luiz Bonamigo   +5 more
wiley   +1 more source

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

open access: yesAdvanced Science, Volume 13, Issue 24, 27 April 2026.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin   +2 more
wiley   +1 more source

FRAX (Australia) scores in women with impaired fasting glucose and diabetes

open access: yesBone Reports, 2019
Background: Diabetes is associated with higher fracture risk despite higher bone mineral density (BMD), with FRAX® underestimating risk. This study aimed to investigate FRAX score with and without BMD for women with normoglycaemia, impaired fasting ...
Lelia L.F. de Abreu   +4 more
doaj   +1 more source

Ukrainian Version of FRAX: from Creation to Validation

open access: yesBolʹ, Sustavy, Pozvonočnik, 2016
FRAX® is an algorithm that computes 10-year probability of hip fracture and major osteoporotic fractures (hip, humerus, wrist fractures and clinical vertebral fractures) in patients aged 40 years and older. These probabilities are calculated based on age,
V.V. Povoroznуuk   +4 more
doaj   +1 more source

Riesgo de fractura en la cohorte FRODOS. Estudio comparativo de la aplicación del modelo FRAX® español, francés, inglés y sueco

open access: yesRevista de Osteoporosis y Metabolismo Mineral, 2014
Fundamento y objetivos: Los estudios sobre validación del FRAX® en España muestran una infravaloración del riesgo de fracturas osteoporóticas principales (FOP) y predicciones más ajustadas para las fracturas femorales (FF).
Kanterewicz E   +4 more
doaj  

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