Results 151 to 160 of about 1,449 (242)

Evolutionarily conserved hydrophobicity and sterics in TM3/TM4 balance Orai1 pore opening

open access: yesProtein Science, Volume 35, Issue 8, August 2026.
Abstract The calcium (Ca2+) channel Orai1—the pore‐forming subunit of the Ca2+ release‐activated Ca2+ channel—is opened by its physiological activator, the endoplasmic reticulum (ER)‐resident Ca2+ sensor stromal interaction molecule 1 (STIM1) upon ER Ca2+ store‐depletion.
Maximilian Fröhlich   +17 more
wiley   +1 more source

Oxygen Fugacity Buffers and an Interactive Calculator

open access: yesGeochemistry, Geophysics, Geosystems, Volume 27, Issue 8, August 2026.
Abstract Oxygen fugacity buffers are equilibrium phase assemblages that constrain the chemical potential of oxygen. They may be coexisting minerals or fluids, or their metastable extrapolations. Oxygen fugacity values vary as a function of pressure and temperature, such that raw numbers often have little interpretive value.
Michael Anenburg
wiley   +1 more source

A Hybrid ML‐PDE Framework for Predicting Breaking Ocean Waves

open access: yesJournal of Geophysical Research: Machine Learning and Computation, Volume 3, Issue 4, August 2026.
Abstract Wave breaking plays a central role in ocean dynamics, dissipating wave energy and shaping the evolution of the sea surface. Yet, breaking remains difficult to model: envelope‐based models efficiently capture nonlinear wave evolution and are interpretable but exclude breaking, while high‐fidelity direct numerical simulations resolve breaking ...
Y. Liu   +3 more
wiley   +1 more source

Protein kinase Cδ and pharmacomechanical coupling: Re‐envisioning cerebral vascular control

open access: yesThe Journal of Physiology, Volume 604, Issue 15, Page 6324-6347, 1 August 2026.
Abstract figure legend Top, G‐protein coupled receptors trigger electromechanical and pharmacomechanical coupling, the latter via signal transduction pathways that inhibit myosin light chain phosphatase. Middle, the relative contribution of electromechanical and pharmacomechanical coupling varies with the concentration and the vessel area to which ...
Nadia Haghbin   +10 more
wiley   +1 more source

Reconsidering Molecular Docking Practices in Aptamer Research

open access: yesChemBioChem, Volume 27, Issue 14, 29 July 2026.
Benchmarking against the theophylline aptamer crystal structure shows that current docking workflows generate incorrect structures and fail to predict binding specificity, underscoring the need for caution when interpreting docking results in aptamer research. Molecular docking is increasingly used to infer aptamer–target interactions, yet most studies
Yachen Xie, Juewen Liu
wiley   +1 more source

A Dendrite‐Resistant Sodium/Porous‐Carbon Anode for Solid‐State Batteries: Strategies and Challenges for Low‐Pressure Operation

open access: yesChemSusChem, Volume 19, Issue 14, 29 July 2026.
Sodiophilic mesoporous carbon confers a near‐perfect interface between Na metal and ceramic solid electrolytes, while serving as a host for solid Na anodes. This synergy forms a foundational element for sodium solid‐state batteries (Na‐SSBs) in pairing a dendrite‐resistant anode with an inherently (electro)chemically stable ceramic electrolyte.
J. Mark Weller   +5 more
wiley   +1 more source

Optical Phased Arrays on Photonic Integrated Circuit Platforms: Challenges, Opportunities, and Future Applications

open access: yesNanophotonics, Volume 15, Issue 14, 27 July 2026.
Integrated optical phased arrays are emerging as scalable engines for solid‐state beam steering and programmable wavefront control. This Review maps the field from beam‐steering principles and core building blocks to material platforms, system‐level bottlenecks, and application frontiers, highlighting how heterogeneous integration, aperiodic ...
Jingwei Li   +7 more
wiley   +1 more source

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