Results 151 to 160 of about 8,461,599 (350)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Open access : un canvi de paradigma per posar a disposició pública el coneixement. El desenvolupament a Alemanya

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2007
La característica principal d'open access és que l'aprofitament del coneixement procedent de l'àmbit d'educació i ciència, que s'ha fet públic i s'ha produït amb fons públics, és lliure (també en el sentit deThe main characteristic of Open Access ...
Kuhlen, Rainer
doaj  

Autonomous Power Decision for the Grant Free Access MUSA Scheme in the mMTC Scenario. [PDF]

open access: yesSensors (Basel), 2020
Ameur WB   +4 more
europepmc   +1 more source

Mobile robot for marking free access floors at construction sites

open access: hybrid, 2019
Takehiro Tsuruta   +2 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Características de repositório educacional aberto para usuários de língua brasileira de sinais

open access: yesTransinformação
O objetivo desse artigo é identificar as características que um repositório educacional aberto deve apresentar para atender as necessidade de informação dos alunos surdos e ouvintes do curso Letras Libras na modalidade a distância da Universidade Federal
Romario Antunes da Silva   +1 more
doaj  

Free Open Access [PDF]

open access: yesMedical Principles and Practice, 2013
openaire   +1 more source

Agriculture versus fish – Norway in WTO [PDF]

open access: yes
The Norwegian agriculture is highly protected and subsidised. The opposite is the case for fisheries and fish farming which suffer from foreign market restrictions.
Gaasland, Ivar
core  

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