Results 111 to 120 of about 2,120,300 (293)
The Effect of Project Types and Technologies on Software Developers' Efforts [PDF]
Considering intrinsic valuation of software developers as the main motive for participating in open source projects, we examine the (Nash) equilibrium effort levels of the software developers in implementing projects that follow one of the three ...
Byung Cho Kim, Dongryul Lee
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The LaTeX project: A case study of open-source software [PDF]
This is a case study of TeX, a typesetting software that was developed by Donald E. Knuth in the late 70's. Released with an open source license, it has become a reference in scientific publishing. TeX is now used to typeset and publish much of the world'
Alexandre Gaudeul
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Free and open source software in Turkey
, 2021 In recent years, there has been growing interest of governments and ï¬rms for Freeand Open Source Software (FOSS). However, FOSS is still a puzzlement for a widespectrum of academic disciplines. Social scientists ask why FOSS hackers partici-pate in FOSS if they do not get any monetary rewards. On the other hand ï¬rms ask,how a ï¬rm can earn money from
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Open Source/Open Course Learning: Lessons for Educators from Free and Open Source Software [PDF]
, 2006 Free/Open Source Software (FOSS) has transformed the software industry. As noted by other authors in this issue, academic information technology (IT) is already realizing many benefits by adopting open software; such benefits include reduced cost ...
Stephenson, Robert
core +2 more sources
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Advancing Economic Research on the Free and Open Source Software Mode of Production [PDF]
Early contributions to the academic literature on free/libre and open source software (F/LOSS) movements have been directed primarily at identifying the motivations that account for the sustained and often intensive involvement of many people in this non-
Jean-Michel Dalle +3 more
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