Results 71 to 80 of about 304,586 (264)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Enhancing Dynamic Performance in K-Rb-²¹Ne Co-Magnetometers through Atomic Density Optimization

Photonics
The K-Rb-21Ne co-magnetometer exhibits poorer dynamic performance due to the larger equivalent magnetic field generated by alkali metal atoms. In this study, the impact of the atomic number density of alkali metal atoms and noble gas atoms in the cell on
Lv Yang, Haoying Pang, Wei Quan
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Interfacing an array of single atom tweezers with fiber guided mode

Applied Physics Express
We demonstrate a one-dimensional array of single atoms interfaced with an optical nanofiber (ONF) using optical tweezers. Single atoms are deterministically trapped in free space and along a 300 nm diameter ONF with tunable atom number and spacing ...
Puthanveettil Bhavya, Kei Iidawa, Makoto Morinaga, Kali P. Nayak   +3 more
doaj   +1 more source

Characterizing Atoms that Result from Decomposition by Clique Separators

Discussiones Mathematicae Graph Theory, 2017
A graph is defined to be an atom if no minimal vertex separator induces a complete subgraph; thus, atoms are the graphs that are immune to clique separator decomposition.
McKee Terry A.
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Optimized measurement-free and fault-tolerant quantum error correction for neutral atoms

Physical Review Research
A major challenge in performing quantum error correction (QEC) is implementing reliable measurements and conditional feed-forward operations. In quantum computing platforms supporting unconditional qubit resets, or a constant supply of fresh qubits ...
Stefano Veroni, Markus Müller, Giacomo Giudice   +2 more
doaj   +1 more source

Heralded mapping of photonic entanglement into single atoms in free space: proposal for a loophole-free Bell test

New Journal of Physics, 2013
An obvious way to entangle two atoms located at remote locations is to produce a pair of entangled photons half-way between the two atoms, to send one photon to each location and to subsequently map the photonic entanglement into the atoms.
Nicolas Sangouard, Jean-Daniel Bancal, Philipp Müller, Joyee Ghosh, Jürgen Eschner   +4 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source