Assessment of carnitine excretion and its ratio to plasma free carnitine as a biomarker for primary carnitine deficiency in newborns [PDF]
JIMD Reports, 2023 In the Netherlands, newborns are referred by the newborn screening (NBS) Program when a low free carnitine (C0) concentration (
Loek L. Crefcoeur +4 more
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Possible correlation between increased serum free carnitine levels and increased skeletal muscle mass following HCV eradication by direct acting antivirals [PDF]
Scientific Reports, 2021 We aimed to evaluate factors associated with changes in skeletal muscle mass in hepatitis C virus (HCV)-infected patients after treatment with direct-acting antivirals (DAAs). Consecutive HCV-infected patients after treatment with DAA were recruited into
Yoshimasa Tokuchi +20 more
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Associations between acylcarnitine to free carnitine ratio and adverse prognosis in heart failure patients with reduced or preserved ejection fraction. [PDF]
ESC Heart Fail, 2017 The failing heart is accompanied by disturbed energy metabolism with mitochondrial dysfunction. Carnitine transports fatty acids into mitochondria for β‐oxidation.
Yoshihisa A +8 more
europepmc +4 more sources
Free Carnitine Measurement [PDF]
Definitions, 2020 National Cancer Institute
semanticscholar +3 more sources
Acylcarnitine to Free Carnitine Ratio Measurement [PDF]
Definitions, 2020 National Cancer Institute
semanticscholar +3 more sources
227 PLASMA FREE CARNITINE LEVELS IN CHILDREN WITH MALNUTRITION [PDF]
Pediatric Research, 1994 In this study plasma free carnitine and albumin levels were measured in children with protein energy malnutrition (PEM). A total of 71 children with malnutrition were studied. The control group consisted of 20 healthy children. Mean plasma carnitin leve1 was 78.4±1.94 nmol/ml in the control group.
Fato Tanzer, Selim Uzunsel, Ayçe Atalay
semanticscholar +3 more sources
Screening of free carnitine and acyl-carnitine status in patients with Familial Mediterranean Fever [PDF]
Pediatr Rheumatol Online J, 2015 Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurring self-limited fever, abdominal pain and chest pain caused by serositis. FMF mainly affects Middle-East populations with a high prevalence in Sephardic Jews, Turkish, Arabs and Armenians.
Kiykim E +6 more
europepmc +4 more sources
Determination of plasma free carnitine by electrospray tandem mass spectrometry [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2001 We have evaluated a tandem mass spectrometry method for determining free carnitine concentrations in plasma and have compared its performance with that of an existing radioenzymatic assay. In this method, plasma was mixed with an internal standard, carnitine-d3 (600 nmol/L), and butylated before analysis on a Quattro II tandem mass spectrometer.
David T Hardy +2 more
semanticscholar +4 more sources
Identification of TMAO-producer phenotype and host–diet–gut dysbiosis by carnitine challenge test in human and germ-free mice [PDF]
Gut, 2018 Objective The gut microbiota-derived metabolite, trimethylamine N-oxide (TMAO) plays an important role in cardiovascular disease (CVD). The fasting plasma TMAO was shown as a prognostic indicator of CVD incident in patients and raised the interest of ...
Wei‐Kai Wu +20 more
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Evaluation of Serum Carnitine Levels for Pediatric Patients Receiving Carnitine-Free and Carnitine-Supplemented Parenteral Nutrition [PDF]
Hospital Pharmacy, 2014 Purpose Carnitine is a carrier molecule transporting long-chain fatty acids (LCFAs) into the mitochondria for fatty acid β-oxidation. The purpose of this study is to evaluate the role of carnitine supplementation in parenteral nutrition (PN) within the pediatric population.
Brian Winther +3 more
openalex +4 more sources