Results 121 to 130 of about 43,342 (295)

CSF carnitine is a potential biomarker in paediatric tuberculous meningitis

open access: yesScientific Reports
The poor outcome of tuberculous meningitis (TBM) is largely due to the difficulty of diagnosis caused by nonspecific symptoms and the absence of specific and sensitive tests.
Ontefetse Neo Plaatjie   +4 more
doaj   +1 more source

The biology of PKM2 in the metabolism and senescence in diabetic kidney disease

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Diabetic kidney disease (DKD) is one of the most common causes of chronic kidney disease that leads to end‐stage kidney disease, and its progression is closely linked to metabolic stress within renal tubular cells. Under long‐term hyperglycemia, cells shift their glucose metabolism from normal oxidative phosphorylation toward glycolysis.
Md. Imrul Kayes, Keizo Kanasaki
wiley   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall   +4 more
wiley   +1 more source

Effect of a homemade diet compared to a commercial diet on glycaemic variability and glycaemic control assessed by continuous glucose monitoring system in diabetic dogs: a randomised crossover study

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives To evaluate the effects of a homemade diet and a commercial diet on glycaemic control and glycaemic variability of diabetic dogs monitored with the FreeStyle Libre continuous glucose monitoring system. Materials and Methods Prospective randomised crossover study including ten client‐owned diabetic dogs on insulin treatment with good ...
A. M. Tardo   +7 more
wiley   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet   +8 more
wiley   +1 more source

Recent advancements in artificial intelligence‐powered cancer prediction from oral microbiome

open access: yesPeriodontology 2000, EarlyView.
Abstract Oral cancer is a major global health burden, ranking sixth in prevalence, with oral squamous cell carcinoma (OSCC) being the most common type. Importantly, OSCC is often diagnosed at late stages, underscoring the need for innovative methods for early detection.
Negin Soghli   +4 more
wiley   +1 more source

Trimethylamine N‐oxide is elevated in postmenopausal women relative to age‐matched men and premenopausal women among individuals with obesity

open access: yesExperimental Physiology, EarlyView.
Abstract Trimethylamine N‐oxide (TMAO) is linked to arterial stiffness and atherosclerosis. Cardiovascular disease (CVD) risk increases following menopause in women. Whether menopause influences plasma TMAO metabolism to mediate CVD risk is unknown.
Daniel J. Battillo, Steven K. Malin
wiley   +1 more source

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