Results 161 to 170 of about 4,359,350 (361)

Pulmonary Vascular Endothelial Cells in Lung Diseases: Mechanisms, Therapeutic Strategies, and Future Directions

Cell Proliferation, EarlyView.
The pathogenic mechanisms of pulmonary vascular endothelial cells (VECs) in lung diseases and their multimodal therapeutic strategies. ABSTRACT Pulmonary vascular endothelial cells (VECs) are essential for the normal function of the lung, through maintaining vascular barrier integrity, regulating blood flow, and participating in inflammatory responses ...
Qianyue Liu, Hongshuai Zheng, Jing Liu, Ming Gao, Faquan Lin, Lin Liao   +5 more
wiley   +1 more source

CSF carnitine is a potential biomarker in paediatric tuberculous meningitis

Scientific Reports
The poor outcome of tuberculous meningitis (TBM) is largely due to the difficulty of diagnosis caused by nonspecific symptoms and the absence of specific and sensitive tests.
Ontefetse Neo Plaatjie, A. Marceline Tutu van Furth, Regan Solomons, Martijn van der Kuip, Shayne Mason   +4 more
doaj   +1 more source

Plasma free carnitine levels in premature and full-term newborns, infants and children [PDF]

, 1980
F Donzelli, P. A. Battistella, L Vergani, E Polidoro, F F Rubaltelli, C. Angelini   +5 more
openalex   +1 more source

Is AMP‐activated protein kinase activation a central mechanism of cardio‐metabolic outcomes after metabolic and bariatric surgery?

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity. It usually results in spectacular weight loss, associated with improvements of obesity‐associated comorbidities. The mechanisms underlying these benefits are not fully understood but could involve a postoperative activation of the enzyme 5′ AMP‐activated ...
Adrien Delcour, Nathalie Niederhoffer
wiley   +1 more source

Sertraline-Associated Riboflavin-Responsive Lipid Storage Myopathy: Report of Two Case. [PDF]

Muscle Nerve
Sertraline exposure can lead to an acquired riboflavin‐responsive multiple acyl‐CoA dehydrogenase deficiency (MADD). In patients with this acquired form of MADD, riboflavin supplementation can even lead to full clinical recovery and marked serological recovery before discontinuation of sertraline.
Shaibani A, Taylor A.
europepmc   +2 more sources

The depletion of serine beta‐lactamase‐like protein (LACTB) ameliorates metabolic dysfunction–associated steatotic liver disease by reducing ubiquitin‐mediated degradation of carnitine palmitoyltransferase 2

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) represents one of the most common chronic liver disorders worldwide, and its incidence continues to rise each year. Serine β‐lactamase‐like protein (LACTB) is a serine protease that plays a crucial role in lipid metabolism and hepatocellular carcinoma, but its function in ...
Wujiang Shi, Xin Liu, Nan Wang, Qianwen Zhang, Jianjun Gao, Canghai Guan, Yapeng Li, Chengru Yang, Shaowu Bi, Xinlei Zou, Xiangyu Zhong   +10 more
wiley   +1 more source

The Protective Effect of L-carnitine on Ionizing Radiation-induced Free Oxygen Radicals

, 2014
Dikmen Dökmeci, Meryem Akpolat, Nurettin Aydoĝdu, Cem Uzal, Latife Doğanay, Fatma Nesrin Turan   +5 more
openalex   +1 more source

Effect of high fat feeding on metabolic efficiency and mitochondrial oxidative activity in adult rats. [PDF]

, 2003
BARLETTA, ANTONIO, Botta M., CRESCENZO, RAFFAELLA, IOSSA, SUSANNA, Lionetti L., LIVERINI, GIOVANNA, MOLLICA, MARIA PINA   +6 more
core   +2 more sources

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

The FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott, Patricia Baumgarten, Thorsten Henning, Daniela Weber, Iwona Wallach, Jana Grune, Ulrich Kintscher, Hermann‐Georg Holzhütter, Tilman Grune, Nikolaus Berndt   +9 more
wiley   +1 more source

Biochemical effects of the hypoglycaemic compound pent-4-enoic acid and related non-hypoglycaemic fatty acids. Effects of the free acids and their carnitine esters on coenzyme A-dependent oxidations in rat liver mitochondria [PDF]

, 1973
Paul C. Holland, H. S. A. Sherratt
openalex   +1 more source