Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Journal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli +12 more
wiley +1 more source
Octanoyl-carnitine predicts post operative complications following coronary artery bypass surgery. [PDF]
Sci RepBahr PA +7 more
europepmc +1 more source
Pediatrics International, Volume 68, Issue 1, January/December 2026.Abstract Background The combination of thiopurines and partial enteral nutrition (TP/PEN) is a common maintenance therapy for mild‐to‐moderate Crohn's disease (CD) in pediatric patients. However, no studies have investigated the efficacy of TP/PEN. This study aimed to evaluate the non‐relapse and complete mucosal healing rates in pediatric CD patients ...
Emiri Kaji +9 more
wiley +1 more source
The vital impact of acetyl-L-carnitine and selenium-fortified <i>Saccharomyces cerevisiae</i> on biochemical parameters in Awassi ewes. [PDF]
Open Vet JAbdulazeez ST, Alsaadi SAA.
europepmc +1 more source
The Role of Innate Lymphoid Cells in the Pathogenesis of Hepatic Echinococcosis: A Literature Review
Parasite Immunology, Volume 48, Issue 1, January 2026.ABSTRACT Hepatic echinococcosis (HE), a major zoonotic disease, remains endemic in pastoral regions of Western China, where its incidence is closely linked to geographical, livestock and sanitary conditions. The disease presents a significant clinical challenge due to the complexity of host–parasite interactions and a high recurrence rate. To date, the
Wei Ma +3 more
wiley +1 more source
Ammonium Hydroxide Enhancement of Dietary Protein in High-Fat Diets Modulates Liver Metabolism Signaling in a Sex- and Age-Dependent Manner in C3H/HeJ Mice. [PDF]
Int J Mol SciBarr BR +4 more
europepmc +1 more source
Stress Nutrition in Aquatic Animals: From Definition to Practice
Reviews in Aquaculture, Volume 18, Issue 1, January 2026.ABSTRACT Aquaculture faces numerous challenges, with stress being one of the major issues that lead to growth loss, metabolic disorders, weakened immunity, redox imbalance, and organ damage in aquatic animals. Nutritional intervention is one of the effective strategies to address these problems. Traditional research has primarily focused on the impacts
Jian Zhang +8 more
wiley +1 more source
The multifaceted roles of ketones in physiology
Experimental Physiology, Volume 111, Issue 1, Page 1-13, 1 January 2026.Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili +3 more
wiley +1 more source
<b>Gut‒heart axis: emerging therapies targeting trimethylamine</b> <b>N-oxide production</b>. [PDF]
Gut MicrobesTorres ER, Wilcox J, Tang WHW.
europepmc +1 more source
Experimental Physiology, Volume 111, Issue 1, Page 69-97, 1 January 2026.Abstract Type 2 diabetes mellitus (T2DM) is a common metabolic disorder characterized by chronic hyperglycaemia, with physical inactivity and excessive adiposity as predisposing factors. This clinical trial aimed to investigate the effects of an exercise intervention on the metabolome of T2DM participants, fasting and in response to an oral glucose ...
Maartje Cox +8 more
wiley +1 more source