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Serum Free Carnitine, Carnitine Esters and Lipids in Patients on Peritoneal Dialysis and Hemodialysis

American Journal of Nephrology, 1986
Serum free and esterified carnitine levels as well as lipids were investigated in patients undergoing regular hemodialysis (HD) treatment before and during 12 weeks of treatment with L-carnitine (1 g i.v.) at the end of each HD. The results were compared with those obtained in patients on continuous ambulatory peritoneal dialysis (CAPD; n = 15) or ...
C, Wanner   +4 more
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Free carnitine and acylcarnitine levels in sera of alcoholics

Biochemical Medicine and Metabolic Biology, 1990
We report the free, acyl-, and total carnitine contents of 49 clinically healthy volunteers and 167 chronic alcoholics with various clinically and/or anatomopathologically identified degrees of hepatic affection. There was a gradual upward trend in carnitine levels as the degree of hepatic affection increased.
C, Alonso de la Peña   +5 more
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Carnitine Depletion During Chronic Hemodialysis: Effect of Substitution on Free Carnitine Plasma Levels

1987
Carnitine plays a role in the oxidative metabolism of free fatty-acids by transporting long chain fatty acids into the mitochondrial matrix (1). During chronic hemodialysis, a depletion of plasma carnitine levels has been observed and attributed to dialysis of this unbound low-molecular weight substance (M.W. 161) (2, 3).
P E, Broquet   +4 more
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Improved methodology to assay carnitine and levels of free and total carnitine in human plasma

Biochemical and Biophysical Research Communications, 1991
Carnitine, once known as vitamin Bt, is intrinsic to human tissue and is biochemically established as being acylated with fatty acids by Acyl-CoA to give Acyl-carnitines which then are transported to the inner mitochondrial membrane by a translocase.
L J, Xia, K, Folkers
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Studies on the distribution of free carnitine and the occurrence and nature of bound carnitine

Archives of Biochemistry and Biophysics, 1962
Abstract The distribution of carnitine in various tissues of the rat was investigated, using modifications of existing assays. Muscle showed about 120–180 μ./g. wet weight; brain, 20 μg.; liver 60–90 μg.; testes, 115 μg. Various treatments with organic solvents and acids released no increased amounts of carnitine. All carnitine was dialyzable.
M A, MEHLMAN, G, WOLF
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Free carnitine levels in children with steroid–sensitive nephrotic syndrome

Pediatrics International, 2002
Abstract Background : Carnitine transports long‐chain fatty acids accross the inner mitochondrial membrane. Carnitine metabolism is disturbed in some renal diseases, such as chronic renal failure. Previous studies have shown that children had normal serum free carnitine (FC) and total carnitine levels in idiopathic nephrotic ...
Gousseinov, A   +4 more
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Free carnitine and acetyl carnitine plasma levels and their relationship with body muscular mass in athletes

Amino Acids, 1998
The purpose of the present study was to investigate the relationship between plasma carnitine concentration and body composition variation in relation to muscular and fat masses since there is no experimentally proved correlation between plasma carnitine and body masses. We used bioelectric impedance analysis (BIA), to determine body composition and to
R. GATTI   +3 more
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Free and Total Carnitine Concentrations in Pig Plasma after Oral Ingestion of Various L-Carnitine Compounds

International Journal for Vitamin and Nutrition Research, 2005
This study was undertaken to investigate the bioavailability of various L-carnitine esters (acetyl-L-carnitine and lauroyl-L-carnitine) and salts (L-carnitine L-tartrate, L-carnitine fumarate, L-carnitine magnesium citrate) relative to base of free L-carnitine.
Klaus, Eder   +3 more
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Carnitine palmitoyltransferase I deficiency in neonate identified by dried blood spot free carnitine and acylcarnitine profile

Journal of Inherited Metabolic Disease, 2001
AbstractA neonate at risk for hepatic carnitine palmitoyltransferase I (L‐CPT I) deficiency was investigated from birth. The free carnitine and acylcarnitine profile in dried whole blood filter paper samples collected at ages 1 and 4 days showed a markedly elevated concentration of free carnitine (141 and 142 μmol/L, respectively), normal ...
K G, Sim   +3 more
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Serum free carnitine levels in children with recurrent pulmonary infections

Pediatrics International, 1997
AbstractThe serum free carnitine levels of 33 children with recurrent pulmonary infection and 30 healthy children were measured and found to be 26.12 ± 0.98 nmol/mL and that of the control group 38.98 ± 0.79 nmol/mL on the average. The mean free carnitine level was statistically determined to be significantly lower when compared with that of the ...
Ergur, AT, Tanzer, F, Cetinkaya, O
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