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Plasma and urine free L-Carnitine in human diabetes mellitus
Acta Diabetologica Latina, 1981L-carnitine is essential for the transport of long-chain fatty acids into mitochondria and their oxidation. Recently, a relationship between plasma free fatty acids (FFA) and L-carnitine metabolism has been observed. Plasma free L-carnitine (FC), FFA, triglycerides, cholesterol, blood glucose concentration and daily excretion of FC were determined in ...
E, De Palo +5 more
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Renal handling of free and acylcarnitine in secondary carnitine deficiency
Neurology, 1984Free and acylcarnitine in serum and urine samples were measured in miscellaneous diseases, including mitochondrial cytopathy with Fanconi's syndrome (MCFS). The urinary concentration of acylcarnitine always exceeded that of free carnitine, and a significant negative correlation was found between the ratio of serum free to acylcarnitine and the ratio of
Y, Ohtani, S, Nishiyama, I, Matsuda
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Serum total and free carnitine levels in children with asthma
World Journal of Pediatrics, 2009Serum carnitine is decreased in recurrent pulmonary infections. We aimed to evaluate serum carnitine levels in asthmatic children.Study group consisted of children with stable asthma and those with acute asthma attacks, while control group included healthy children. Attack severity was determined by the pulmonary score system.
Karaman, Oezkan +4 more
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l‐Carnitine May Attenuate Free Fatty Acid‐Induced Endothelial Dysfunction
Annals of the New York Academy of Sciences, 2004Abstract: We have recently shown that elevated levels of free fatty acid (FFA) seen in insulin‐resistant obese subjects are associated with endothelial dysfunction. l‐Carnitine, which is required for mitochondrial FFA transport/oxidation, has been reported to improve vascular function in subjects with diabetes and heart disease.
Sudha S, Shankar +3 more
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Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 2006
Carnitine has an essential role in the mitochondrial oxidation of long-chain fatty acids. Carnitine deficiency has been described in patients with chronic kidney disease. Total carnitine (TC) deficiency or a lower-than-normal ratio of free carnitine to acylated carnitine (FC:AC) has been shown to be associated with disorders in metabolism and plasma ...
Veronica B, Marín +5 more
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Carnitine has an essential role in the mitochondrial oxidation of long-chain fatty acids. Carnitine deficiency has been described in patients with chronic kidney disease. Total carnitine (TC) deficiency or a lower-than-normal ratio of free carnitine to acylated carnitine (FC:AC) has been shown to be associated with disorders in metabolism and plasma ...
Veronica B, Marín +5 more
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Annals of the Rheumatic Diseases, 2015
Background Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurring self-limited fever, abdominal pain and chest pain caused by serositis (1). FMF mainly affects Middle-East populations with a high prevalence in Sephardic Jews, Turkish, Arabs and Armenians (2).
E. Kiykim +6 more
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Background Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by recurring self-limited fever, abdominal pain and chest pain caused by serositis (1). FMF mainly affects Middle-East populations with a high prevalence in Sephardic Jews, Turkish, Arabs and Armenians (2).
E. Kiykim +6 more
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Levels of Seminal Free L(-) Carnitine in Fertile and Infertile Men
Journal of Urology, 1984Data about the levels of free L‐carnitine, an epididymal marker in human semen, are contradictory and unclear, particuliarly in their releationship to fertility. This can perhaps be explained by the absence of any studies of seminal L‐carnitine in a large group of fertile men, and by the lack of consideration of factors influencing its secretion.In ...
J C, Soufir +6 more
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Annals of the Rheumatic Diseases, 2015
Background Juvenile idiopathic arthritis (JIA) is not a single disease; it9s group of all arthritis with unknown etiology, starting before 16 years of age and lasting at least 6 weeks long. JIA is the most common rheumatic disease in childhood. Carnitine is an important molecule in cellular energy metabolism.
E. Kıykım +6 more
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Background Juvenile idiopathic arthritis (JIA) is not a single disease; it9s group of all arthritis with unknown etiology, starting before 16 years of age and lasting at least 6 weeks long. JIA is the most common rheumatic disease in childhood. Carnitine is an important molecule in cellular energy metabolism.
E. Kıykım +6 more
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Free radical-mediated damage and carnitine esters
1995It is now well recognized that oxygen free radicals are involved in the tissue damage occurring upon reperfusion after an ischemic period. Although it is quite obvious that oxygen supply must be restored as soon as possible, this beneficial effect is counteracted by the generation of free oxygen radicals.
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Free and total carnitine in human serum after oral ingestion of L-carnitine.
Diabete & metabolisme, 1983Twelve students with in apparent good health and fasting since the previous evening ingested 2 g of L-carnitine on one day and a placebo on another day in a single-blind trial. Six blood samples were taken during the 24 h following the ingestion. Their blood carnitine levels increased (the free form by 81%, and the total by 57%) to a maximum at about 3.
A C, Bach +3 more
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