Results 31 to 40 of about 43,342 (295)

Determinação dos níveis da carnitina no plasma sua importância no estudo em doentes com doenças neuromusculares.

Acta Médica Portuguesa, 2002
L-carnitine plays a major role in the transport of the long chain fatty acids for the beta-oxidation in the mitochondria. The deficiency of the carnitine is associated by the deficit of the beta-oxidation of the long chain fatty acids and so a different ...
Maria Cíntia Siqueira, Fernando Morgado
doaj   +1 more source

Association of Abnormal Serum L-Carnitine Levels with Idiopathic Changes in Left Ventricular Geometry in Pediatric and Adolescent Patients [PDF]

Iranian Journal of Medical Sciences, 2022
Background: There is no compelling evidence to prove an association between serum free L-carnitine levels and changes in left ventricular (LV) geometry. The present study aimed to evaluate a possible association between these parameters.
Mohsen Shahidi, Khaled Rahmani, Abdorrahim Afkhamzadeh   +2 more
doaj   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility.

PLoS ONE, 2020
BackgroundLow carnitine status may underlie the development of insulin resistance and metabolic inflexibility. Intravenous lipid infusion elevates plasma free fatty acid (FFA) concentration and is a model for simulating insulin resistance and metabolic ...
Yvonne M H Bruls, Yvo J M Op den Kamp, Esther Phielix, Lucas Lindeboom, Bas Havekes, Gert Schaart, Esther Moonen-Kornips, Joachim E Wildberger, Matthijs K C Hesselink, Patrick Schrauwen, Vera B Schrauwen-Hinderling   +10 more
doaj   +1 more source

Blood carnitine profiling on tandem mass spectrometry in liver cirrhotic patients

BMC Gastroenterology, 2020
Background The level and profiles of blood free carnitine and acylcarnitines, obtained by acylcarnitine analysis using tandem mass spectrometry, reflect various metabolic conditions.
Hisamitsu Miyaaki, Hironori Kobayashi, Satoshi Miuma, Masanori Fukusima, Ryu Sasaki, Masafumi Haraguchi, Kazuhiko Nakao   +6 more
doaj   +1 more source

Failure of carnitine in improving hepatic nitrogen content in alcoholic and non-alcoholic malnourished rats

Clinics, 2010
AIMS: To investigate the effect of carnitine supplementation on alcoholic malnourished rats' hepatic nitrogen content. METHODS: Malnourished rats, on 50% protein-calorie restriction with free access to water (malnutrition group) and malnourished rats ...
Luciana P. Rodrigues, Guilherme Vannucchi Portari, Gilberto João Padovan, Alceu Afonso Jordão, Vivian Suen, Julio Sergio Marchini   +5 more
doaj   +1 more source

Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women

BMC Pregnancy and Childbirth, 2010
Background It has been shown that plasma carnitine concentrations decrease markedly during gestation. A recent study performed with a low number of subjects suggested that this effect could be due to a low iron status which leads to an impairment of ...
Seliger Gregor, Hanisch Nicole, Ringseis Robert, Eder Klaus   +3 more
doaj   +1 more source

Serum free carnitine levels during valproic acid therapy

The Indian Journal of Pediatrics, 1997
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Tütüncüoglu S., Tekgül H., Levent E., Hüseyinov A.   +3 more
openaire   +4 more sources

Carnitine exchange in the assessment of tissue energetics and physical performance of young athletes

Спортивная медицина: наука и практика, 2020
Objective: to develop prognostic criteria for assessing the physical performance of children engaged in different sports, using the features of carnitine metabolism.
N. V. Rylova, A. A. Biktimirova, A. V. Zholinsky   +2 more
doaj   +1 more source