A Requirement for Fatty Acid Oxidation in the Hormone-Induced Meiotic Maturation of Mouse Oocytes [PDF]
, 2013 We have previously shown that fatty acid oxidation (FAO) is required for AMP-activated protein kinase (PRKA)-induced maturation in vitro. In the present study, we have further investigated the role of this metabolic pathway in hormone-induced meiotic ...
Downs, Stephen, Valsangkar, Deepa
core +2 more sources
Acute Exercise Stimulates Carnitine Biosynthesis and OCTN2 Expression in Mouse Kidney
Kidney & Blood Pressure Research, 2017 Background/Aims: Carnitine is essential for the transport of long-chain FAs (FA) into the mitochondria for energy production. During acute exercise, the increased demand for FAs results in a state of free carnitine deficiency in plasma.
Tom L. Broderick +3 more
doaj +1 more source
Primary carnitine deficiency in a neonate
Archives of Medicine and Health Sciences, 2021 Carnitine deficiency in paediatrics can present in infants with episodes of irritability, lethargy and hepatomegaly. The main treatment for primary carnitine deficiency is to take L-carnitine supplements.
Manish Rasania +3 more
doaj +1 more source
Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? [PDF]
, 2016 Background: Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis.
Bosch, Guido +13 more
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Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Acta Médica Portuguesa, 2002 L-carnitine plays a major role in the transport of the long chain fatty acids for the beta-oxidation in the mitochondria. The deficiency of the carnitine is associated by the deficit of the beta-oxidation of the long chain fatty acids and so a different ...
Maria Cíntia Siqueira, Fernando Morgado
doaj +1 more source
Association of Abnormal Serum L-Carnitine Levels with Idiopathic Changes in Left Ventricular Geometry in Pediatric and Adolescent Patients [PDF]
Iranian Journal of Medical Sciences, 2022 Background: There is no compelling evidence to prove an association between serum free L-carnitine levels and changes in left ventricular (LV) geometry. The present study aimed to evaluate a possible association between these parameters.
Mohsen Shahidi +2 more
doaj +1 more source
Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]
, 2018 Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A. +8 more
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Blood carnitine profiling on tandem mass spectrometry in liver cirrhotic patients
BMC Gastroenterology, 2020 Background The level and profiles of blood free carnitine and acylcarnitines, obtained by acylcarnitine analysis using tandem mass spectrometry, reflect various metabolic conditions.
Hisamitsu Miyaaki +6 more
doaj +1 more source
A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines [PDF]
, 2018 Background: The outstanding performance of an elite athlete might be associated with changes in their blood metabolic profile. The aims of this study were to compare the blood metabolic profiles between moderate- and high-power and endurance elite ...
A Boldyrev +51 more
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