Results 81 to 90 of about 43,342 (295)

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

Effects of Pemafibrate on Serum Carnitine and Plasma Myostatin in Patients With Metabolic Dysfunction Associated Steatotic Liver Disease

JCSM Communications
Background Pemafibrate, a selective peroxisome proliferator‐activated receptor alpha (PPARα) modulator (SPPARMα), has positive effects on liver‐related markers (e.g., liver stiffness determined by magnetic resonance elastography and alanine ...
Ryohei Tanigawa, Atsushi Nakajima, Yuichiro Eguchi, Hirokazu Takahashi, Rohit Loomba, Hideki Suganami, Masaya Tanahashi, Hidenori Arai   +7 more
doaj   +1 more source

Enzymatic Determination of Free Carnitine in Milk and Infant Formulas

Journal of AOAC INTERNATIONAL, 1995
Abstract A simple spectrophotometric assay for free carnitine in milk and supplemented infant formulas has been developed. After acid extraction, carnitine is measured enzymatically through its reaction with carnitine acetyltransferase coupled with acetyl coenzyme A and dithiobenzoate (DTNB).
H E, Indyk, D C, Woollard
openaire   +2 more sources

l-carnitine in critically ill patients—a case series study

Renal Replacement Therapy, 2018
Background l-carnitine is essential for lipid metabolism, and lack of l-carnitine intake and loss by treatments lead to carnitine depletion causing muscle weakness, anemia, and immune dysfunction.
Takehiko Oami, Taku Oshima, Noriyuki Hattori, Ayako Teratani, Saori Honda, Toshihiko Yoshida, Shigeto Oda   +6 more
doaj   +1 more source

Correlation between acylcarnitine/free carnitine ratio and cardiopulmonary exercise test parameters in patients with incident dialysis. [PDF]

Front Physiol, 2023
Ito W, Uchiyama K, Mitsuno R, Sugita E, Nakayama T, Ryuzaki T, Takahashi R, Katsumata Y, Hayashi K, Kanda T, Washida N, Sato K, Itoh H.   +12 more
europepmc   +1 more source

Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma.

PLoS ONE, 2020
BACKGROUND:Fatigue is a common adverse event during lenvatinib treatment in patients with hepatocellular carcinoma. One mechanism contributing to development of fatigue might involve abnormal adenosine triphosphate synthesis that is caused by carnitine ...
Hironao Okubo, Hitoshi Ando, Kei Ishizuka, Ryuta Kitagawa, Shoki Okubo, Hiroaki Saito, Shigehiro Kokubu, Akihisa Miyazaki, Kenichi Ikejima, Shuichiro Shiina, Akihito Nagahara   +10 more
doaj   +1 more source

Risk factors for carnitine deficiency in critically ill adults: A descriptive cross‐sectional study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Critical illness is a risk factor for carnitine deficiency. Carnitine deficiency may result in serious medical complications and poor clinical outcomes. This study aimed to identify the prevalence and potential predictors of carnitine deficiency.
Jennifer Gordon, Rebecca Brody, Hamed Samavat, Mireille Hamdan, Alexander L. Colonna, Jason B. Young, Laura D. Byham‐Gray   +6 more
wiley   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira, Caíque Olegário Diniz e Magalhães, Elizabeth Luciana Marinho Miguel, Larissa Vieira Toledo, Débora Ribeiro Orlando, Alan Rodrigues Teixeira Machado, Bruno Del Bianco Borges, Luciano José Pereira, Marco Fabrício Dias‐Peixoto, Eric Francelino Andrade   +9 more
wiley   +1 more source

Altered maternal thyroid function: Effect of L-carnitine supplementation on fetal and neonatal myocardial free fatty acid oxidation,in vitro [PDF]

, 1998
Ratan Kumar
openalex   +1 more source

Serum-free carnitine levels in children with heart failure.

Journal of tropical pediatrics, 1999
WOS ...
Ergur, AT, Tanzer, F, Cetinkaya, O
openaire   +3 more sources