Results 131 to 140 of about 1,439,807 (264)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Basic fibroblast growth factor preserves rabbit adipose-derived mesenchymal stromal cells in serum-free culture. [PDF]

J Vet Sci
Kuncorojakti S, Aswin A, Diyantoro D, Susilowati H, Yudaniayanti IS, Susanti L, Rodprasert W.   +6 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A serum-free culture medium for long-term expansion of human airway basal stem cells. [PDF]

Stem Cell Res Ther
Jiang M, Zhu Y, Zheng H, Chen H, Luo W, Deng Z, Zhang H, Su Z, Li S, Ma N.   +9 more
europepmc   +1 more source

Development of a Serum-Free Culture Method for Endothelial Cells of the Stria Vascularis and Their Pro-Inflammatory Secretome Changes Induced by Oxidative Stress. [PDF]

Clin Exp Otorhinolaryngol, 2023
Yi Y, Wang XR, Chen HT, Huang WY, Feng LX, Fang SB, Xiong GX.   +6 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Next-generation full-thickness human skin models produced using 3D electrospun scaffolds and animal-component-free culture media. [PDF]

Front Toxicol
Hayden PJ, Chakravarty J, Hodroj RK, Lindner SR, Fitzgerald LM, Le Do JT, Keng HT, Patel V, Behrsing HP, Phaneuf MD.   +9 more
europepmc   +1 more source

Development and evaluation of a novel xeno-free culture medium for human-induced pluripotent stem cells. [PDF]

Stem Cell Res Ther, 2022
Hua Y, Yoshimochi K, Li J, Takekita K, Shimotsuma M, Li L, Qu X, Zhang J, Sawa Y, Liu L, Miyagawa S.   +10 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Serum coating enables feeder-free culture of naive human pluripotent stem cells preserving developmental potential. [PDF]

EMBO J
Rossignoli G, Oberhuemer M, Brun IS, Zorzan I, Osnato A, Wenzel A, van Genderen E, Drusin A, Panebianco G, Magri N, Becker M, Solis MA, Colantuono C, van Knippenberg SSFA, Pham TXA, Khodeer S, Grumati P, Cacchiarelli D, Martini P, Rivron N, Pasque V, Żylicz JJ, Leeb M, Martello G.   +23 more
europepmc   +1 more source