Results 31 to 40 of about 27,457 (262)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Laser phase errors in seeded free electron lasers

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2012
Harmonic seeding of free electron lasers has attracted significant attention as a method for producing transform-limited pulses in the soft x-ray region. Harmonic multiplication schemes extend seeding to shorter wavelengths, but also amplify the spectral
D. Ratner, A. Fry, G. Stupakov, W. White
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Formation of electron bunches for harmonic cascade x-ray free electron lasers

open access: yesPhysical Review Special Topics. Accelerators and Beams, 2006
Specific requirements for the electron beam in harmonic cascade-free electron lasers, together with means to produce such beams, are presented. All results are illustrated with simulations and particle tracking studies.
M. Cornacchia   +3 more
doaj   +1 more source

Radio-Frequency Undulators, Cyclotron Auto Resonance Maser and Free Electron Lasers

open access: yesApplied Sciences, 2021
We discuss a hybrid Free Electron Laser (FEL) architecture operating with a RF undulator provided by a powerful Cyclotron Auto-Resonance Maser (CARM). We outline the design elements to operate a compact X-ray device.
Emanuele Di Palma   +5 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Real-time tracking of the intramolecular vibrational dynamics of liquid water

open access: yesCommunications Chemistry
Water’s polarity and hydrogen-bond network give rise to its unique chemical and biochemical behaviour. Its vibrational motions, occurring on a few-femtosecond timescale, govern ultrafast energy transfer within the hydrogen-bond network.
Gaia Giovannetti   +15 more
doaj   +1 more source

Free electron laser.

open access: yesThe Review of Laser Engineering, 1987
Concepts and historical review of free electron laser are reported. Since the experiment at Stanford University was successful in 1977, great numberof FEL experiments with various accelerators were successfully performed to observe amplification and oscillation of radiations in the wavelength range of 0.5 μm-103μm.
openaire   +2 more sources

The Quantum Free-Electron Laser [PDF]

open access: yes, 2018
CERN Yellow Reports: School Proceedings, Vol 1 (2018): Proceedings of the CAS-CERN Accelerator School on Free Electron Lasers and Energy Recovery ...
openaire   +3 more sources

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