Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
High efficiency tapered free-electron lasers with a prebunched electron beam
In this paper we analyze the high gain, high efficiency tapered free-electron laser amplifier with a prebunched electron beam. Simple scaling laws are derived for the peak output power and extraction efficiency and verified using 1D simulations.
C. Emma +4 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth +6 more
wiley +1 more source
Low‐Angle Grain Boundaries and Re‐Segregation in Single‐Crystalline Ni‐Base Superalloys
This work demonstrates that Re‐segregation at low‐angle grain boundaries (LAGBs) in Ni‐base superalloys is influenced by misorientation angle. Advanced microscopy and atom probe tomography reveal that higher misorientation angles increases Re‐segregation.
Alireza B. Parsa +9 more
wiley +1 more source
Active FEL-Klystrons as Formers of Femto-Second Clusters of Electromagnetic Field. Description of Models on the Basis of Sections of ‘Ordinary’ FEL’: Analisys [PDF]
Physical processes of ultrashort electromagnetic cluster formation in multiharmonic parametrical free electron lasers are analyzed. The conditions, which are necessary for formation of such clusters, are found out.
V.V. Kulish, A.V. Lysenko, A.Ju. Brusnik
doaj
Linear optics correction for linacs and free electron lasers
Linear optics errors in the linac, the transport line, and the undulator section of a free electron laser (FEL) can significantly impact the FEL performance.
Tong Zhang, Xiaobiao Huang, Tim Maxwell
doaj +1 more source
Minimum Spectral Bandwidth in Echo Seeded Free Electron Lasers
This paper examines the impact of non-linear longitudinal phase distortions on the spectral bandwidth in echo seeded free electron lasers (FELs). It extends the existing theory developed in Hemsing [1] for echo-enabled harmonic generation (EEHG) to ...
Erik Hemsing
doaj +1 more source
Creating Ti–Fe α/β Alloys by Diffusion‐Driven Solid‐State Processing
This study proposes making alloys containing fast diffusing elements that are difficult to produce by ingot metallurgy, by diffusion‐driven solid‐state HIP processing of elemental powders and low‐temperature homogenisation. Here, novel Fe‐Ti α–β alloys are formed having fine α–β lamellae, a small β prior grain size without significant intermetallics ...
Jiaqi Xu +10 more
wiley +1 more source

