Results 51 to 60 of about 1,367,655 (261)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A Complexity Science Account of Humor

open access: yesEntropy, 2023
A common assumption of psychological theories of humor is that experienced funniness results from an incongruity between stimuli provided by a verbal joke or visual pun, followed by a sudden, surprising resolution of incongruity.
Wolfgang Tschacher, Hermann Haken
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Unified Classical Thermodynamics: Primacy of Dissymmetry over Free Energy

open access: yesThermo
In thermodynamic theory, free energy (i.e., available energy) is the concept facilitating the combined applications of the theory’s two fundamental laws, the first and the second laws of thermodynamics.
Lin-Shu Wang
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Control of Overfitting with Physics

open access: yesEntropy
While there are many works on the applications of machine learning, not so many of them are trying to understand the theoretical justifications to explain their efficiency.
Sergei V. Kozyrev   +2 more
doaj   +1 more source

Study on the Magnetic-machine Coupling Characteristics of Giant Magnetostrictive Actuator Based on the Free Energy Hysteresis Characteristics

open access: yesSensors, 2018
A giant magnetostrictive actuator presents advantages such as large strain, high precision, and quick response. It is a hotly debated research topic in the field of micro drivers; however, the nonlinear intrinsic relationship between its output and input
Zhen Yu, Tao Wang, Min Zhou
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Capacitive Mixing for Harvesting the Free Energy of Solutions at Different Concentrations

open access: yesEntropy, 2013
An enormous dissipation of the order of 2 kJ/L takes place during the natural mixing process of fresh river water entering the salty sea. “Capacitive mixing” is a promising technique to efficiently harvest this energy in an environmentally clean and ...
Renéa van Roij   +5 more
doaj   +1 more source

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