Results 71 to 80 of about 5,295,129 (293)

Energy and helicity budgets of solar quiet regions

open access: yes, 2014
We investigate the free magnetic energy and relative magnetic helicity budgets of solar quiet regions. Using a novel non-linear force-free method requiring single solar vector magnetograms we calculate the instantaneous free magnetic energy and relative ...
Georgoulis, M. K.   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Control of Overfitting with Physics

open access: yesEntropy
While there are many works on the applications of machine learning, not so many of them are trying to understand the theoretical justifications to explain their efficiency.
Sergei V. Kozyrev   +2 more
doaj   +1 more source

Study on the Magnetic-machine Coupling Characteristics of Giant Magnetostrictive Actuator Based on the Free Energy Hysteresis Characteristics

open access: yesSensors, 2018
A giant magnetostrictive actuator presents advantages such as large strain, high precision, and quick response. It is a hotly debated research topic in the field of micro drivers; however, the nonlinear intrinsic relationship between its output and input
Zhen Yu, Tao Wang, Min Zhou
doaj   +1 more source

The Magnetic Energy - Helicity Diagram of Solar Active Regions

open access: yes, 2012
Using a recently proposed nonlinear force-free method designed for single vector magnetograms of solar active regions we calculate the instantaneous free magnetic energy and relative magnetic helicity budgets in 162 vector magnetograms corresponding to ...
Georgoulis, Manolis K.   +2 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Capacitive Mixing for Harvesting the Free Energy of Solutions at Different Concentrations

open access: yesEntropy, 2013
An enormous dissipation of the order of 2 kJ/L takes place during the natural mixing process of fresh river water entering the salty sea. “Capacitive mixing” is a promising technique to efficiently harvest this energy in an environmentally clean and ...
Renéa van Roij   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Potential fields of free energy at the stages of hardening and softening of the Hencky medium at nonpositivity of volume deformation

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2014
The Hencky medium with softening under isothermal and quasistatic deformation is considered. It is believed that volume deformation is not positive. In this case softening is characterized by the part of union curve with negative slope.
Kirill V Berdnikov, Valery V Struzhanov
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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