Results 71 to 80 of about 1,381,598 (313)
Umbrella Sampling Simulations of Carbon Nanoparticles Crossing Immiscible Solvents
Molecules, 2022 We use molecular dynamics to compute the free energy of carbon nanoparticles crossing a hydrophobic–hydrophilic interface. The simulations are performed on a biphasic system consisting of immiscible solvents (i.e., cyclohexane and water).
Anastasios Gotzias
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Unified Classical Thermodynamics: Primacy of Dissymmetry over Free Energy
ThermoIn thermodynamic theory, free energy (i.e., available energy) is the concept facilitating the combined applications of the theory’s two fundamental laws, the first and the second laws of thermodynamics.
Lin-Shu Wang
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Free energy predictions for crystal stability and synthesisability
, 2022 What is the likelihood that a hypothetical material - the combination of a composition and crystal structure - can be formed? Underpinning the reliability of predictions for local or global crystal stability is the choice of thermodynamic potential. Here,
Alex M., Ganose +3 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Control of Overfitting with Physics
EntropyWhile there are many works on the applications of machine learning, not so many of them are trying to understand the theoretical justifications to explain their efficiency.
Sergei V. Kozyrev +2 more
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Sensors, 2018 A giant magnetostrictive actuator presents advantages such as large strain, high precision, and quick response. It is a hotly debated research topic in the field of micro drivers; however, the nonlinear intrinsic relationship between its output and input
Zhen Yu, Tao Wang, Min Zhou
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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Capacitive Mixing for Harvesting the Free Energy of Solutions at Different Concentrations
Entropy, 2013 An enormous dissipation of the order of 2 kJ/L takes place during the natural mixing process of fresh river water entering the salty sea. “Capacitive mixing” is a promising technique to efficiently harvest this energy in an environmentally clean and ...
Renéa van Roij +5 more
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