Results 61 to 70 of about 10,102,387 (234)
The free energy principle made simpler but not too simple [PDF]
, 2023 This paper provides a concise description of the free energy principle, starting from a formulation of random dynamical systems in terms of a Langevin equation and ending with a Bayesian mechanics that can be read as a physics of sentience.
Sajid, N +6 more
core +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
About the Carbon Free Boston team [PDF]
, 2020 List of principle investigators for the Carbon Free Boston ...
Institute for Sustainable Energy, Boston University
core +1 more source
Multiscale Free Energy Analysis of Human Ecosystem Engineering
Entropy, 2021 Unlike ecosystem engineering by other living things, which brings a relatively limited range of sensations that are connected to a few enduring survival preferences, human ecosystem engineering brings an increasing variety and frequency of novel ...
Stephen Fox
doaj +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Energy principle for stability of general force-free MHD equilibria
, 1982 An energy principle has been constructed for the determination of stability of general force-free equilibria against ideal- and dissipative-(tearing)-MHD modes. The concept of accessible neighbouring equilibria, with the inclusion of singular currents on
T.H. Jensen, J.K. Lee, M.S. Chu
core +1 more source
Active Inference and Epistemic Value in Graphical Models
Frontiers in Robotics and AI, 2022 The Free Energy Principle (FEP) postulates that biological agents perceive and interact with their environment in order to minimize a Variational Free Energy (VFE) with respect to a generative model of their environment. The inference of a policy (future
Thijs van de Laar +5 more
doaj +1 more source