Results 51 to 60 of about 8,605,845 (299)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dynamic gas supply mechanism and theoretical production modes of free gas-rich deep coal reservoirs
Meitian dizhi yu kantanObjective and Methods The production processes of adsorbed and free gases and the dynamic partitioning mechanism behind the production efficiency of both gas types are critical scientific issues to be addressed urgently in the exploration and production ...
Shida CHEN +6 more
doaj +1 more source
Frontiers in Earth Science, 2022 Free gas saturation is one of the key factors that affect the overall production behaviors of hydrate reservoirs. For example, different free gas contents could alter the thermal response of hydrate reservoirs to the artificial stimulation and hence ...
Shouding Li +16 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Dissociating Gas Hydrate Beneath the Hydrate Stability Zone
Geophysical Research LettersVast amounts of carbon are stored beneath the seafloor in the form of methane hydrate. Hydrate is stable at moderate pressure and low temperature at a depth extending several hundred meters beneath the seafloor to the base of gas hydrate stability (BGHS)
I. A. Pecher +14 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 2017 Two sectors, Itata and Valdivia, which are located in the Chilean margin were analysed by using seismic data with the main purpose to characterize the gas hydrate concentration.
Vargas Cordero Iván +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Petroleum Exploration and DevelopmentBased on the test and experimental data from exploration well cores of the Upper Paleozoic in the central-eastern Ordos Basin, combined with structural, burial depth and fluid geochemistry analyses, this study reveals the fluid characteristics, gas ...
Shida CHEN +9 more
doaj +1 more source