Results 51 to 60 of about 2,650,105 (305)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Discrete fracture model with unsteady-state adsorption and water–gas flow for shale-gas reservoirs

Energy Reports, 2023
A shale-gas reservoir possesses many complex characteristics, including coexisting free and adsorbed gases, a complex distribution of fractures, and the existence of movable water in these fractures.
Bin Chang, Cheng Cao, Yunde Zhang, Baofeng Lan   +3 more
doaj   +1 more source

Cosmic rays and the primordial gas

, 2007
One of the most outstanding problems in the gravitational collapse scenario of early structure formation is the cooling of primordial gas to allow for small mass objects to form.
Abel, Abel, Aldrovandi, Bakker, Benedetta Ciardi, Biermann, Black, Cen, Cen, Ciardi, Dalgarno, De Jong, Diehl, Donahue, Dove, Enßlin, Galli, Ginzburg, Glover, Gould, Groom, Haiman, Haiman, Hartquist, Heitler, Hirata, Janev, Jasche, Jens Jasche, Karpas, Mannheim, Martin, Miniati, Oneil, Osterbrock, Osterbrock, Peebles, Peskin, Pfrommer, Ripamonti, Roberge, Shapiro, Shchekinov, Shull, Smith, Smith, Spitzer, Spitzer, Stanev, Sternheimer, Tegmark, Thielens, Torsten A. Enßlin, Weiss, Whaling, Wise, Yousif, Ziegler   +57 more
core   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Dissociating Gas Hydrate Beneath the Hydrate Stability Zone

Geophysical Research Letters
Vast amounts of carbon are stored beneath the seafloor in the form of methane hydrate. Hydrate is stable at moderate pressure and low temperature at a depth extending several hundred meters beneath the seafloor to the base of gas hydrate stability (BGHS)
I. A. Pecher, A. E. Cook, E. A. Solomon, X. Wang, S. Han, M. Paganoni, M. Luo, K. U. Heeschen, D. D. McNamara, M. Nole, L. LeVay, K. Petronotis, P. M. Barnes, L. M. Wallace, D. M. Saffer   +14 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Recoil Free Scattering From a Free Gas

, 2008
9 pages, 2 ...
Sanders, Scott N., Mintert, Florian, Heller, Eric J.   +2 more
openaire   +2 more sources

Molecular dynamics studies of anomalous transport in rarefied gas flows [PDF]

, 2010
We investigate the thermodynamically non-equilibrium gas dynamics by measuring molecular free path distribution functions, inter-molecular collision rates and wall dependent mean free path (MFP) profiles using the molecular dynamics (MD) method.
Dongari, Nishanth, Reese, Jason, Zhang, Yonghao   +2 more
core  

Local Group Dwarf Galaxies: Nature And Nurture [PDF]

, 2011
We investigate the formation and evolution of dwarf galaxies in a high resolution, hydrodynamical cosmological simulation of a Milky Way sized halo and its environment.
Annibali, Bernard, Besla, Boylan-Kolchin, Bruzual, Cecilia Scannapieco, Davis, Einasto, Faber, Flynn, Geha, Gilmore, Gnedin, Governato, Grebel, Grebel, Guo, Haardt, Johnston, Klimentowski, Koleva, Koposov, Lavery, Li, Mateo, Mayer, Mayer, Meurer, Michielsen, Monelli, Murali, Navarro, Okamoto, Okamoto, Peñarrubia, Piatek, Revaz, Sawala, Sawala, Scannapieco, Scannapieco, Scannapieco, Schwartz, Simon White, Smith, Springel, Springel, Springel, Springel, Stinson, Strigari, Sutherland, Sánchez-Janssen, Till Sawala, Tissera, Tollerud, Tolstoy, Tremaine, Valcke, Wadepuhl, Walker, Whiting, Woo, Xue   +63 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source