Results 111 to 120 of about 7,845,575 (284)
DISTORTION IN FREE NILPOTENT GROUPS [PDF]
We prove that a subgroup of a finitely generated free nilpotent group F is undistorted if and only if it is a retract of a subgroup of finite index in F.
openaire +3 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Let \(F_k\) be a free group of rank \(k\). Let \(\overline g\) and \(\overline h\) be \(n\)-tuples of \(F_2\) which satisfy the same existential formulas. It is proved here that there exists an automorphism of \(F_2\) which maps \(\overline g\) to \(\overline h\). The following results are typical: (1) Fix a prime \(p\).
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Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A Characterization of Procyclic Groups via Complete Exterior Degree
We describe the nonabelian exterior square G∧^G of a pro-p-group G (with p arbitrary prime) in terms of quotients of free pro-p-groups, providing a new method of construction of G∧^G and new structural results for G∧^G.
Bernardo G. Rodrigues +1 more
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Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Some Remarks on Commuting Fixed Point Free Automorphisms of Groups
In this article we will find necessary and sufficient conditions for a fixed point free automorphism (fpf automorphism) of a group to be a commuting automorphism. F
M Akhavan-Malayeri
doaj

