Results 91 to 100 of about 688,287 (309)

Le concept d'union économique dans la Constitution canadienne : de l'intégration commerciale à l'intégration des facteurs de production [PDF]

, 1979
The object of this paper is to assess the constitutional position as to economic integration within Canada. Following a short review of'the basic elements of economic integration, it proceeds to analyse the law and practice relating to the free ...
Bernier, Ivan
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Constructing Europe Through Mobility

Cuadernos Europeos de Deusto, 2017
Promoting mobility through the development of the principle of free movement of people, goods, services and capital has been a cornerstone of the European integration process.
Ander Audikana, Vincent Kaufmann
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Free movement in the European Union: the case of Great Britain

Halyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì, 2016
In this paper the authors consider the free movement of goods, services and capital within the European Union as a case of the Great Britain. Also, an article devoted to the role of Britain in the European Union, addresses the issue of EU enlargement in
Е. Chukubayev
doaj  

Europäisch-türkische Warenverkehrsfreiheit

Türk-Alman Üniversitesi Hukuk Fakültesi Dergisi, 2022
„Man verliebt sich nicht in einen Binnenmarkt ohne Grenzen“ – sagte der langjährige EU-Kommissionspräsident Jacques Delors. Dabei ist der gemeinsame Markt durch freien Warenverkehr politisch „eine der Erfolgsgeschichten des europäischen Einigungswerks ...
Thomas Wilrich
doaj  

Brexit i jego skutki dla Niemiec z perspektywy ekonomicznej i społecznej [PDF]

, 2019
At the end of March 2017, the British government initiated the legal procedure of withdrawal from the EU, beginning the two-year countdown towards Brexit. However, as of August 2019, the final outcome of the Brexit negotiations is still pending.
Bartkowiak, Marcin, Ratajczak, Anna
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

The influence of Free-Trade on the environmental effects of transportation. Scale-, Technique- and Composition-Effects [PDF]

, 2007
The changeover from a situation of Autarky to a situation of Free- Trade alters the trade and production patterns of the participating countries which in turn affects the transportation-sector.
Vannoni, Stefan
core   +2 more sources