Results 81 to 90 of about 166,193,329 (284)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Labor migration and unemployment: what can we learn from EU rules on the free movement of workers? CEPS Liberty and Security in Europe No. 46, 7 February 2012 [PDF]
, 2012 This paper examines the impact of labour migration on unemployment in the context of the accession of Bulgaria and Romania to the EU and the EU’s rules on the free movement of workers. In particular, it addresses two questions.
Guild, Elspeth, Carrera, Sergio
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European Papers(Series Information) European Papers - A Journal on Law and Integration, 2025 10(1), 55-96 | Article | (Table of Contents) 1. Introduction. – 2. A quick look at border and other types of checks. – 3. An overview of the two systems. – 3.1. Hungary’s EKAER.
Szilárd Gáspár-Szilágyi +1 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Free movement of people in European Union
, 2014 Free movement of people in European Union is a legal bases of the right of free movement that in the European Union treaty providing an internal market with no restriction.
Onwe, Ugochukwu Bishop
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Free movement in the European Union: the case of Great Britain
Halyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì, 2016 In this paper the authors consider the free movement of goods, services and capital within the European Union as a case of the Great Britain. Also, an article devoted to the role of Britain in the European Union, addresses the issue of EU enlargement in
Е. Chukubayev
doaj
Trade in services of member states of the Eurasian Economic Union
RUDN Journal of Economics, 2019 The Treaty on the Eurasian Economic Union, which became effective since January 1, 2015, establishes the principles and the purposes of integration consolidation and also provides free movement of goods, services, the capital and labor power in the ...
Kuanysh N. Yelikbaev
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Rights resulting from the free movement of workers
, 2018 The European Union (EU) is an international organisation which now consists of 28 countries with a population around 508 million people. I t is a very powerful organization, but it can only exercise as much power as the Member States give to it. The EU'
Rybalkina, Valeria
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