Results 61 to 70 of about 18,052 (297)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Free movement of goods: A comparative analysis of the European community treaty and the north American free trade agreement [PDF]

open access: yes, 2003
The European Union is currently an economic union, which means that it has almost removed every internal barrier to trade, therefore achieving the free circulation of all factors of production (goods, services, capital, and persons) across the union. The
Perichart, Pedro A.
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

FİVE DECADES PLEDGE FOR TURKEY: ANKARA AGREEMENT AND BEYOND

open access: yesJournal of Smart Economic Growth, 2017
The Association Agreement between Turkey and the European Community set the goal of establishing a Customs Union between the Parties in a 3-stages process, with the hope of Turkey’s eventual membership to the European Economic Community. Despites Customs
Sibel MEHTER AYKIN, Ileana TACHE
doaj  

Free movement of goods - analysis of the free movement of tobacco products [PDF]

open access: yes, 2019
Sloboda kretanja roba je osnova za funkcioniranje europskoga unutarnjeg tržišta. Ograničenja koja utječu na odvijanje toga procesa mogu biti novčane i nenovčane prirode.
Uglešić, Franka
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Free Movement of Goods and the Czech Republic with Emphasis on Environmental Protection [PDF]

open access: yes
After the accession to the European Union, the Czech Republic became a part of the largest market in the world, the Single European Market. The Czech Republic has to keep the single market rules as set in the Treaty and secondary legislation.
Magdaléna, Kudelová
core   +1 more source

Free Movement of Goods: a Comparative Analysis of the European Community Treaty and the North American Free Trade Agreement [PDF]

open access: yes, 2005
The European Union is currently an economic union, which means that it has almost removed every internal barrier to trade, therefore achieving the free circulation of all factors of production (goods, services, capital, and persons) across the union. The
Perichart, Pedro A
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Effects of Tax Competition [PDF]

open access: yesTheoretical and Applied Economics, 2010
Tax competition between governments is a research topic of growing importance in the context of globalization. This subject is particularly important for the European Union, characterized by a high degree of economic integration, single currency and free
Ioan TALPOŞ, Alexandru O. CRÂŞNEAC
doaj   +1 more source

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