Results 41 to 50 of about 18,052 (297)

Rights resulting from the free movement of workers [PDF]

open access: yes, 2018
The European Union (EU) is an international organisation which now consists of 28 countries with a population around 508 million people. I t is a very powerful organization, but it can only exercise as much power as the Member States give to it. The EU'
Rybalkina, Valeria
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Challenges related to security and protection of the EU’s financial interests in the context of the Customs Union Reform [PDF]

open access: yesPrzegląd Europejski
The foundation of the European Union's activities in the field of free movement of goods and customs handling of goods is the customs union. The aim of the article is to analyse the construction principles of the customs union in the field of trade in ...
Ewa Gwardzińska
doaj   +1 more source

Gloss to the Judgment of the Court of Justice of 17 November 2022, C‑224/20

open access: yesStudia Prawnicze KUL, 2023
The commented judgment concerns the admissibility of repackaging medicinal products in parallel trade. It was issued in connection with new EU regulations aimed at counteracting the counterfeiting of such products. The Court examined how the regulations
Krzysztof Dobieżyński
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

What Keck and Mithouard Should Have Said: It Could Have Been So Simple

open access: yesEuropean Papers, 2023
(Series Information) European Papers - A Journal on Law and Integration, 2023 8(1), 385-391 | What Should Have Said | (Abstract) This rewriting of Keck and Mithouard maintains the basic underlying philosophy of the Keck judgment but dispenses with the ...
Stefan Enchelmaier
doaj   +1 more source

19. Derogation from the free movement of goods [PDF]

open access: yes, 2017
This chapter examines the provisions of Article 36 of the Treaty on the Functioning of the European Union (TFEU) containing the derogation from the free movement of goods.
Philippa Watson   +2 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

What Keck and Mithouard Should Have Said: Preventing Substantial Barriers to Market Access

open access: yesEuropean Papers, 2023
(Series Information) European Papers - A Journal on Law and Integration, 2023 8(1), 363-372 | What Should Have Said | (Abstract) This rewriting of Keck and Mithouard is based on three categories of measures having equivalent effect: (1) national measures
Niklas Nachtnebel   +3 more
doaj   +1 more source

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