Results 31 to 40 of about 11,409,895 (265)

Oxidative Stress in Transthyretin-Mediated Amyloidosis: An Exploratory Study

Antioxidants
Transthyretin-mediated amyloidosis (ATTR) is a systemic disease with protein precipitation in many tissues, mainly the peripheral nerve and heart. Both genetic (ATTRv, “v” for variant) and wild-type (ATTRwt) forms are known. Beyond the steric encumbrance,
Marco Fiore, Chiara Cambieri, Laura Libonati, Federica Moret, Edoardo D’Andrea, Maria Grazia Di Certo, Claudio Passananti, Francesca Gabanella, Nicoletta Corbi, Matteo Garibaldi, Cristina Chimenti, Maria Alfarano, Giampiero Ferraguti, Silvia Francati, Maurizio Inghilleri, Marco Ceccanti   +15 more
doaj   +1 more source

Effect of combined antioxidant treatment on oxidative stress, muscle damage and sport performance in female basketball players [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. We determined the impact of antioxidant supplementation by GE132R on sports performance, oxidative stress markers, and muscle enzymes activities in professional female basketball players. Methods.
Baralić Ivana, Stojmenović Tamara, Anđelković Marija, Đorđević Brižita, Dikić Nenad, Radojević-Škodrić Sanja, Pejić Snežana   +6 more
doaj   +1 more source

Insights into Mechanisms of Blood-Brain Barrier Permeability – Roles of Free Radicals, Matrix Metalloproteinsases, and Caveolin-1

, 2014
Free radicals, including reactive oxygen species (ROS) and reactive nitrogen species (RNS), are important mediators in cerebral ischemia-reperfusion injury and other neurological diseases.
Shen, J, Jiangang Shen, Gu, Y, Yong Gu
core   +1 more source

Protective factors against oxygen free radicals and hydrogen peroxide in rheumatoid arthritis synovial fluid [PDF]

, 1984
Oxygen free radicals are probably involved in the pathogenesis of rheumatoid arthritis (RA). The enzymes involved in protection against oxygen free radicals and H2O2 (superoxide dismutase, catalase, and glutathione peroxidase) were measured.
Koster, J.F. (Johan), Swaak, A.J.G. (Antonius), Biemond, P. (Pieter), Antonius J. G. Swaak, Pieter Biemond, Johan F. Koster   +5 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

Oxygen free radicals in rheumatoid arthritis [PDF]

, 1986
Current knowledge strongly suggests that oxygen free radicals are involved in the pathogenesis of RA. Additional information about the mechanism of free radical attack is necessary in order to find out if interaction with the mechanism of free radical ...
Biemond, P. (Pieter)
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation [PDF]

, 2007
Ischemia is a major cause of brain damage, and patient management is complicated by the paradoxical injury that results from reoxygenation. We have now explored the generation of reactive oxygen species (ROS) in hippocampal and cortical neurons in ...
SCORZIELLO, ANTONELLA, Abramov, A.Y., Duchen, M.R., Abramov AY, Scorziello, A., Duchen MR   +5 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The effect of intravitreal bevacizumab and transpupillary thermotherapy on choroidal metastases and literature review

Indian Journal of Ophthalmology, 2015
Aims : To represent the effects of transpupillary thermotherapy (TTT) and intravitreal bevacizumab on choroidal metastases and review the literature. Settings and Design : A retrospective, interventional, noncomparative case series. Materials and Methods
Chun-Ju Lin, Yi-Yu Tsai
doaj   +1 more source