Results 41 to 50 of about 11,409,895 (265)

Oxygen free radicals and reperfusion injury; the effect of ischaemia and reperfusion on the cellular ability to neutralise oxygen toxicity

, 1986
Oxygen free radicals and reperfusion injury; the effect of ischaemia and reperfusion on the cellular ability to neutralise oxygen ...
CECONI, Claudio, A. Cargnoni, D. Medici, S. Curello, FERRARI, Roberto   +4 more
core   +1 more source

Stunned myocardium and oxygen free radicals. Sarcolemmal membrane damage due to oxygen free radicals. [PDF]

, 1991
"Reperfusion after reversible ischemia has been shown to result in prolonged depression of contractile function (""myocardial stunning""). Recent studies suggest that oxygen free radicals may mediate postischemic dysfunction.
Kobayashi, Akira, NARANJAN S DHALLA, Hayashi, Hideharu, NOBORU YAMAZAKI, Yamazaki, Noboru, Naranjan, S. Dhalla, Kaneko, Masanori, MASANORI KANEKO, HIDEHARU HAYASHI, AKIRA KOBAYASHI   +9 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

An Assessment of Polar Solvent Extraction on Free Scavenging Activity of Sonneratia caseolaris

Journal of Experimental Life Science
Degenerative diseases such as stroke and cancer arise due to oxidative stress by a large number of reactive oxygen species (ROS) in the body. Free radical scavenging (antioxidant) compounds are needed to neutralize the ROS.
Feni Iranawati, Yoan Oktavia, Rarasrumdyah Kasitowati, Hartati Kartikaningsih, Ledhyane Ika Harlyan, Sunanto Arifin   +5 more
doaj   +1 more source

CZK, a novel alkaloid derivative from Clausena lansium, alleviates ischemic stroke injury through Nrf2-mediated antioxidant effects

Scientific Reports, 2023
Anti-oxidant stress is a potential strategy for the treatment of ischemic stroke. Here, we found a novel free radical scavenger termed as CZK, which is derived from alkaloids contained in Clausena lansium.
Haodong Chen, Yangbo Liu, Juling Feng, Hongyun Wang, Yantao Yang, Qidi Ai, Zhao Zhang, Shifeng Chu, Naihong Chen   +8 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Critical Difference and Biological Variation in Biomarkers of Oxidative Stress and Nutritional Status in Athletes [PDF]

, 2016
The longitudinal monitoring of oxidative stress (OS) in athletes may enable the identification of fatigued states and underperformance. The application of OS biomarker monitoring programs in sport are hindered by reliability and repeatability of in-the ...
Lewis, Nathan A., Franco, Rodrigo, Richard Burden, Howatson, Glyn, Charles R. Pedlar (2547427), Charles R Pedlar, Nathan A Lewis, Glyn Howatson (324877), Pedlar, Charles R., John Newell, Glyn Howatson, Burden, Richard, Lewis, Nathan, Nathan A. Lewis (2547424), Richard Burden (2269660), Newell, John, John Newell (114330), Pedlar, Charles   +17 more
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Antigenotoxic potential of rutin and quercetin in Swiss mice exposed to gamma radiation

Biomedical Journal, 2014
Background: Ionizing radiation induces a variety of genetic damages through the formation free radicals such as reactive oxygen species (ROS). Appropriate antioxidant intervention may inhibit or reduce free radical toxicity and thus offer protection ...
Shrikant L Patil, Nageshwar B Rao, HM Somashekarappa, KP Rajashekhar   +3 more
doaj   +1 more source

Intumescent flame retardant finishing for polypropylene nonwoven fabric

Journal of Industrial Textiles, 2022
This work reports our recent efforts on improving the fire safety of nonwoven polypropylene fabric by increasing surface polarity followed by a conventional finishing.
Peng Qi, Xuefei Wang, Yufei Wang, Xiaoyu Gu, Sheng Zhang   +4 more
doaj   +1 more source