Results 81 to 90 of about 8,503,072 (299)
Relativistic Schrödinger equation and probability currents for free particles
Pracì Mìžnarodnogo Geometričnogo CentruIn this work, we start from the problem of quantizing the relativistic Hamiltonian of a free massive particle (rest mass different from 0), a problem exceptionally difficult in the standard approaches to quantum mechanics.
David Carfì
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Numerical Ruin Probability in the Dual Risk Model with Risk-Free Investments
Risks, 2018 In this paper, a dual risk model under constant force of interest is considered. The ruin probability in this model is shown to satisfy an integro-differential equation, which can then be written as an integral equation. Using the collocation method, the
Sooie-Hoe Loke, Enrique Thomann
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Известия высших учебных заведений: Проблемы энергетики, 2019 : The article presents an algorithm for estimating reliability parameters - probability of failure-free operation time and failure rate of low-voltage switching devices based on statistical data on failures of circuit breakers installed in control and ...
E. I. Gracheva +3 more
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The Topology-Free Construction of the Universal Type Structure for Conditional Probability Systems [PDF]
Electronic Proceedings in Theoretical Computer Science, 2017 We construct the universal type structure for conditional probability systems without any topological assumption, namely a type structure that is terminal, belief-complete, and non-redundant.
Pierfrancesco Guarino
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Union-free Hypergraphs and Probability Theory
European Journal of Combinatorics, 1984 This paper contains new lower and upper bounds on the number of subsets of an n element set one can have so that the union of no two equals that of two others. A new lower bound is obtained when no two unions of any kind are the same; and a new upper bound when no set has the same union with two others.
Frankl, Peter, Föredi, Zoltan
openaire +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source