Results 71 to 80 of about 5,158,059 (301)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Free Probability in a Minimal Quantum Circuit Model

open access: yesPhysical Review X
Recent experimental and theoretical developments in many-body quantum systems motivate the study of their out-of-equilibrium properties through multitime correlation functions. We consider the dynamics of higher-order out-of-time-order correlators (OTOCs)
Felix Fritzsch, Pieter W. Claeys
doaj   +1 more source

INVESTIGATION OF THE PARAMETERS OF RELIABILITY OF LOW VOLTAGE COMMUTATION DEVICES ON OPERATING DATA OF INDUSTRIAL ENTERPRISES

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2019
: The article presents an algorithm for estimating reliability parameters - probability of failure-free operation time and failure rate of low-voltage switching devices based on statistical data on failures of circuit breakers installed in control and ...
E. I. Gracheva   +3 more
doaj   +1 more source

Free completely random measures [PDF]

open access: yes
Free probability is a noncommutative probability theory introduced by Voiculescu where the concept of independence of classical probability is replaced by the concept of freeness.
Francesca Collet, Fabrizio Leisen
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Free Stein kernels and an improvement of the free logarithmic Sobolev inequality

open access: yes, 2017
In their 2015 paper, Ledoux, Nourdin, and Peccati used Stein kernels and Stein discrepancies to improve the classical logarithmic Sobolev inequality (relative to a Gaussian distribution).
Nelson, Brent
core   +1 more source

Free Probability Theory [PDF]

open access: yes, 1996
Free Brownian motion, free stochastic calculus, and random matrices by P. Biane Large $N$ quantum field theory and matrix models by M. R. Douglas Free products of finite dimensional and other von Neumann algebras with respect to non-tracial states by K. Dykema Amalgamated free product $C^*$-algebras and $KK$-theory by E. C.
openaire   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

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