Results 51 to 60 of about 685,164 (300)
Universe, 2022 It was proven that the class of stable interatomic potentials can be represented exactly as a superposition of Yukawa potentials. In this paper, an auxiliary scalar field was introduced to describe the dynamics of a system of neutral particles (atoms) in
Anatoly Yu. Zakharov, Victor V. Zubkov
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Matrix concentration inequalities and free probability
Inventiones mathematicae, 2023 56 ...
Bandeira, Afonso S. +2 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
On the Computation of Spectra in Free Probability
Journal of Functional Analysis, 2001 We use free probability techniques to compute borders of spectra of non hermitian operators in finite von Neumann algebras which arise as `free sums' of `simple' operators. To this end, the resolvent is analyzed with the aid of the Haagerup inequality.
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Asymptotic expansions in the CLT in free probability [PDF]
Probability Theory and Related Fields, 2012 This version contains some small corrections and ...
Chistyakov, Gennadiy, Götze, Friedrich
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Reliability Analysis of Subsystem in Balanced Hypercubes
IEEE Access, 2020 The probability that a multiprocessor computer system has faults arises as the cardinality of the system grows. The subsystem reliability in a system, defined as the probability that there exists a fault-free subsystem of a specified cardinality when the
Qifan Zhang +3 more
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Free fermionic probability theory and k-theoretic schubert calculus
Forum of Mathematics, SigmaFor each of the four particle processes given by Dieker and Warren, we show the n-step transition kernels are given by the (dual) (weak) refined symmetric Grothendieck functions up to a simple overall factor. We do so by encoding the particle dynamics as
Shinsuke Iwao +2 more
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