Results 31 to 40 of about 5,158,059 (301)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Analysis of SIS-SI Stochastic Model with CTMC on the Spread of Malaria Disease
Various mathematical models have been developed to describe the transmission of malaria disease. The purpose of this study was to modify an existing mathematical model of malaria disease by using a CTMC stochastic model.
Niswah Yanfa Nabilah Syams +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Unitary designs have become a vital tool for investigating pseudorandomness, since they approximate the statistics of the uniform Haar ensemble. Despite their central role in quantum information, their relations to quantum chaotic evolution and, in ...
Michele Fava +2 more
doaj +1 more source
THE PROBABILITY DETERMINATION OF ERROR-FREE AIR TRAFFIC CONTROLLER OPERATION
Human error is considered to be a cause or one of the main factors in most accidents. Errors are not a certain type of deviation in behaviour; they are a natural product of all human efforts.
V. E. Borisov +3 more
doaj +1 more source
Matrix concentration inequalities and free probability
56 ...
Bandeira, Afonso S. +2 more
openaire +4 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Characterization problems in free probability
In classical probability there are known many characterization of probability measures by independence properties. The best example of such result is Bernstein's theorem, which says that for independent X and Y, random variables X+Y and X-Y are ...
Szpojankowski, Kamil
core +1 more source
On a Method of Introducing Free-Infinitely Divisible Probability Measures
Random integral mappings give isomorphism between the subsemigroups of the classical (I D, *) and the free-infinite divisible (I D, ⊞) probability measures.
Jurek Zbigniew J.
doaj +1 more source

