Results 61 to 70 of about 685,164 (300)
Critical Care, 2022 Background Timing of initiation of kidney-replacement therapy (KRT) in critically ill patients remains controversial. The Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial compared two ...
Fernando G. Zampieri +11 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Relativistic Schrödinger equation and probability currents for free particles
Pracì Mìžnarodnogo Geometričnogo CentruIn this work, we start from the problem of quantizing the relativistic Hamiltonian of a free massive particle (rest mass different from 0), a problem exceptionally difficult in the standard approaches to quantum mechanics.
David Carfì
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
The Splitting Process in Free Probability Theory [PDF]
International Mathematics Research Notices, 2015 Free cumulants were introduced by Speicher as a proper analog of classical cumulants in Voiculescu's theory of free probability. The relation between free moments and free cumulants is usually described in terms of Moebius calculus over the lattice of non-crossing partitions.
Ebrahimi-Fard, Kurusch +1 more
openaire +2 more sources
Quantum signatures of chaos from free probability
Journal of High Energy PhysicsA classical dynamical system can be viewed as a probability space equipped with a measure-preserving time evolution map, admitting a purely algebraic formulation in terms of the algebra of bounded functions on the phase space.
Hugo A. Camargo +4 more
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Numerical Ruin Probability in the Dual Risk Model with Risk-Free Investments
Risks, 2018 In this paper, a dual risk model under constant force of interest is considered. The ruin probability in this model is shown to satisfy an integro-differential equation, which can then be written as an integral equation. Using the collocation method, the
Sooie-Hoe Loke, Enrique Thomann
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Известия высших учебных заведений: Проблемы энергетики, 2019 : The article presents an algorithm for estimating reliability parameters - probability of failure-free operation time and failure rate of low-voltage switching devices based on statistical data on failures of circuit breakers installed in control and ...
E. I. Gracheva +3 more
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