Results 61 to 70 of about 5,158,059 (301)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Reliability Analysis of Subsystem in Balanced Hypercubes
IEEE Access, 2020 The probability that a multiprocessor computer system has faults arises as the cardinality of the system grows. The subsystem reliability in a system, defined as the probability that there exists a fault-free subsystem of a specified cardinality when the
Qifan Zhang +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Computation of infix probabilities for probabilistic context-free grammars [PDF]
, 2011 The notion of infix probability has been introduced in the literature as a generalization of the notion of prefix (or initial substring) probability, motivated by applications in speech recognition and word error correction.
Satta, Giorgio +4 more
core +2 more sources
Quantum signatures of chaos from free probability
Journal of High Energy PhysicsA classical dynamical system can be viewed as a probability space equipped with a measure-preserving time evolution map, admitting a purely algebraic formulation in terms of the algebra of bounded functions on the phase space.
Hugo A. Camargo +4 more
doaj +1 more source
Relativistic Schrödinger equation and probability currents for free particles
Pracì Mìžnarodnogo Geometričnogo CentruIn this work, we start from the problem of quantizing the relativistic Hamiltonian of a free massive particle (rest mass different from 0), a problem exceptionally difficult in the standard approaches to quantum mechanics.
David Carfì
doaj +1 more source
Universality probability of a prefix-free machine [PDF]
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2012 We study the notion of universality probability of a universal prefix-free machine, as introduced by C. S. Wallace. We show that it is random relative to the third iterate of the halting problem and determine its Turing degree and its place in the arithmetical hierarchy of complexity.
Barmpalias, George, Dowe, David L.
openaire +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Numerical Ruin Probability in the Dual Risk Model with Risk-Free Investments
Risks, 2018 In this paper, a dual risk model under constant force of interest is considered. The ruin probability in this model is shown to satisfy an integro-differential equation, which can then be written as an integral equation. Using the collocation method, the
Sooie-Hoe Loke, Enrique Thomann
doaj +1 more source
Quadratic Forms in Free Probability
, 2017 We investigate various aspects of quadratic forms in free random variables: Characterization problems, distributions and preservation of infinite divisibility. A crucial property in these respects is the phenomenon of cancellation of odd cumulants and we
Lehner, Franz
core +1 more source