Results 41 to 50 of about 1,276,041 (313)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Free product decompositions in images of certain free products of groups
Journal of Algebra, 2007 This interesting paper can be summarized as follows. Let \(F\) be the free product of a finite family \(\mathcal A\) of groups and let \(n=|\mathcal A|\). Let \(m< n\) and let \(R\) be the normal closure in \(F\) of \(m\) elements of \(F\). Let \(R_{\mathcal F}=\bigcap_{K\in \mathcal F}K\), where \(\mathcal F\) is an s-filter, and let \(G=F/R_{\mathcal
Romanovskii, N, Wilson, J
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FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Journal of Education, Health and Sport, 2018 Introduction and aim: Gluten-free diet is a necessary diet in a treatment of gluten-dependent diseases. It means a complete exclusion from the menu of products being a source of gluten.
Natalia Mikołajczak
doaj +3 more sources
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Remote Sensing, 2015 With the high resolution of optical data and the lack of weather effects of passive microwave data, we developed an algorithm to map daily cloud-free fractional snow cover (FSC) based on the Moderate Resolution Imaging Spectroradiometer (MODIS) standard ...
Jie Deng +4 more
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Free Productive Agency: Reasons, Recognition, Socialism
Philosophical Topics, 2020 This paper argues that recognition is, fundamentally, a relationship between a person and a reason. The recognizer acts for a reason, in the interpersonal case, only when she takes the recognizee’s rational intentions—intentions whose content is favored by reasons—as reasons.
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FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source