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Immuno-analytical characteristics of PSA and derived biomarkers (total PSA, free PSA, p2PSA)
Annales de Biologie Clinique, 2023Prostate-specific antigen (PSA) is the recommended tumor marker for individual screening and follow-up of prostate cancer. This paper reviews main structural and physiological data about prostate specific antigen isoforms: total PSA, free PSA, [-2]proPSA (also named p2PSA).
Cédric, Desbène +4 more
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Relevance of total PSA and free PSA prescriptions
Annales de biologie clinique, 2018The total PSA testing has been frequently criticized for its effectiveness in the early detection of prostate cancer. These widely resumed in and out of the medical community have led to a decrease in prescriptions. Recommendations against the use of PSA for screening have been issued in France and in most countries.
Lamy, Pierre-Jean +4 more
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Journal of Addiction Medicine, 2013
Addiction to opium continues to be a major worldwide medical and social problem. The study addressing the association between opium consumption and serum prostate-specific antigen (PSA) level is lacking. We determined the effects of opium consumption on serum PSA levels in opium-addict men.
Mohammad Reza, Safarinejad +5 more
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Addiction to opium continues to be a major worldwide medical and social problem. The study addressing the association between opium consumption and serum prostate-specific antigen (PSA) level is lacking. We determined the effects of opium consumption on serum PSA levels in opium-addict men.
Mohammad Reza, Safarinejad +5 more
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2012
The introduction of PSA in 1987 (Stamey et al. N Engl J Med 317(15):909–16, 1987) as a serum marker for prostate cancer and its subsequent development as a screening test for early detection (Catalona et al. N Engl J Med 324(17):1156–61, 1991) dramatically altered the diagnosis and management of this disease.
Kenneth G. Nepple +2 more
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The introduction of PSA in 1987 (Stamey et al. N Engl J Med 317(15):909–16, 1987) as a serum marker for prostate cancer and its subsequent development as a screening test for early detection (Catalona et al. N Engl J Med 324(17):1156–61, 1991) dramatically altered the diagnosis and management of this disease.
Kenneth G. Nepple +2 more
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Anticancer research, 1997
The normal distribution of values was determined and the age-related reference ranges were established for free PSA, total PSA and free PSA/total PSA ratios.A total of 414 healthy males (14 to 84 years old) were randomly chosen from the Chinese residing in the central area of Taiwan and underwent detailed clinical examinations that included digital ...
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The normal distribution of values was determined and the age-related reference ranges were established for free PSA, total PSA and free PSA/total PSA ratios.A total of 414 healthy males (14 to 84 years old) were randomly chosen from the Chinese residing in the central area of Taiwan and underwent detailed clinical examinations that included digital ...
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Comparative evaluation of total PSA, free/total PSA, and complexed PSA in prostate cancer detection
Urology, 2002To compare the performance of prostate-specific antigen (PSA), the free/total PSA (F/T PSA) ratio, and complexed PSA (cPSA) in prostate cancer detection.Five hundred thirty-five patients evaluated at the UROMED prostate cancer detection clinic had total PSA, free PSA, and cPSA measured before undergoing transrectal ultrasonography and sextant prostate ...
S, Tanguay +5 more
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Clinical usefulness of free and complexed PSA
Scandinavian Journal of Clinical and Laboratory Investigation, 1995We selected serums from 51 fully characterized prostate cancer patients and 48 biopsy-proven BPH patients in order to test the ability of the ratio of the free/total PSA in distinguishing between CaP and BPH patients in the best case scenario. The 51 cancer patients had cancer volumes ranging from 2.0-17.8 mL and had a median % free PSA of 8.9%. The 48
A F, Prestigiacomo, T A, Stamey
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Urology, 2000
To ascertain when the serum determination of the free prostate-specific antigen (PSA)/total PSA (fPSA/tPSA) ratio is clinically useful, and whether the identification of PSA or prostate-specific membrane antigen (PSM) mRNA in circulating cells has diagnostic advantages over the determination of their protein product.fPSA, tPSA, and the fPSA/tPSA ratio ...
BASSO, DANIELA +8 more
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To ascertain when the serum determination of the free prostate-specific antigen (PSA)/total PSA (fPSA/tPSA) ratio is clinically useful, and whether the identification of PSA or prostate-specific membrane antigen (PSM) mRNA in circulating cells has diagnostic advantages over the determination of their protein product.fPSA, tPSA, and the fPSA/tPSA ratio ...
BASSO, DANIELA +8 more
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Urology, 1999
To investigate the relationship between age and total prostate-specific antigen (tPSA), free PSA (fPSA), and percent free PSA (%fPSA) in men 48 to 79 years old without clinical evidence of prostate cancer. We determined age-specific ranges for each parameter and compared the results with previously published studies in similar populations.Nine hundred ...
L A, Kalish, J B, McKinlay
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To investigate the relationship between age and total prostate-specific antigen (tPSA), free PSA (fPSA), and percent free PSA (%fPSA) in men 48 to 79 years old without clinical evidence of prostate cancer. We determined age-specific ranges for each parameter and compared the results with previously published studies in similar populations.Nine hundred ...
L A, Kalish, J B, McKinlay
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