Results 161 to 170 of about 148,412 (201)

The Investigation of Total PSA, Free PSA, and Free/Total PSA Ratio in Patients With Liver Cirrhosis Patients According to Child-Pugh Score

Urology, 2013
To investigate the total prostate-specific antigen (tPSA), free PSA (fPSA), and free/total PSA (fPSA/tPSA) ratio in patients with liver cirrhosis (LC) according to the severity of hepatic insufficiency.Eighty-two male patients with LC were studied. The severity of liver disease was categorized by Child-Pugh score (Child-Pugh A, B, and C). Forty-two age-
Mehmet, Inci, Murat Mehmet, Rifaioglu, Melek, Inci, Murat, Celik, Mehmet, Demir, Turker, Ulutas, Mursel, Davarci, Vicdan Koksaldi, Motor, Ramazan, Davran, Cumali, Gokce   +9 more
openaire   +3 more sources

Comparison of percent free PSA, PSA density, and age-specific PSA cutoffs for prostate cancer detection and staging

Urology, 2000
Various methods have been proposed to increase the specificity of prostate-specific antigen (PSA), including age-specific PSA reference ranges, PSA density (PSAD), and percent free PSA (%fPSA). In this multicenter study, we compared these methods for their utility in cancer detection and their ability to predict pathologic stage after radical ...
W J, Catalona, P C, Southwick, K M, Slawin, A W, Partin, M K, Brawer, R C, Flanigan, A, Patel, J P, Richie, P C, Walsh, P T, Scardino, P H, Lange, G H, Gasior, K G, Loveland, K R, Bray   +13 more
openaire   +2 more sources

Improvement of specificity in PSA‐based screening by using PSA‐transition zone density and percent free PSA in addition to total PSA levels

The Prostate, 1998
The clinical value of prostate-specific antigen (PSA) density in differentiating between prostate cancer and benign prostatic hyperplasia has been the subject of several studies. In this context the question has been raised about the diagnostic benefit of PSA transition-zone density (PSA-TZ density = total PSA/transition-zone volume) in the detection ...
W, Horninger, A, Reissigl, H, Klocker, H, Rogatsch, K, Fink, H, Strasser, G, Bartsch   +6 more
openaire   +2 more sources

PSA Isoforms: [−2]proPSA Significant Adjunct to Free PSA

2009
Prostate-Specific Antigen (PSA) is a widely used serum marker to aid in the diagnosis of prostate cancer and monitor its treatment. PSA by itself has limited specificity, and cannot distinguish between early stage prostate cancer and benign prostatic hyperplasia (BPH), resulting in many unnecessary biopsies.
openaire   +1 more source

1261 Clinical evaluation of specific assays for free PSA and total PSA

European Journal of Cancer, 1995
It is now well known that PSA assays measure simultaneously free PSA (FPSA) and PSA bound to α-1 antichymotrypsin (PSA-ACT). Furthermore specific measurement of the free form gives additional information on PSA in the distinction between benign prostate hypertrophies (BPH) and prostate cancer.
N. Bedeau, L. Bellanger, V. Malard, D. Pons, P. Seguin, J. Guillet   +5 more
openaire   +1 more source

Immunoradiometric Assay of Total PSA, Free PSA and PSA Ratio Calculation in Prostatic Cancer (PCa) Diagnosis

1999
Total PSA assay is a well established procedure for biochemical evaluation and management of PCa which usefulness in its diagnosis is limited by its weak specificity with regard to BPH. Recently the assay of Free-PSA and the calculation of Free/Total-PSA Ratio has been suggested to improve the specificity of PSA in the range of concentrations between 2.
Luca Giovanella, Paola Erba, Luca Ceriani, Patrizia Vio, Silvana Garancini   +4 more
openaire   +1 more source

The behavior of prostate specific antigen (PSA) and free-PSA (f-PSA) under antihormonal therapy.

Anticancer research, 2001
Within a few weeks, if therapy of the hormone sensitive, advanced prostate cancer (PCa) is sufficient, there will be a PSA-decrease to testify to the regression of the PCa. Free-PSA (f-PSA) is used for the differential diagnosis of the PCa. Values under 25% f-PSA in proportion to complete-PSA show the possibility of the existence of a Pca.
H W, Wechsel, R, Gleichmann, J, Blasseneck   +2 more
openaire   +1 more source

Automated Cobas Core PSA assays: sensitive, precise, and specific measurement of PSA-total and PSA-total/PSA-free ratio.

Anticancer research, 1999
We describe the analytical performance of the newly developed Roche Cobas Core PSA Total EIA and the Cobas Core PSA Free EIA. The assays are designed for the random access immunochemistry analyzer Cobas Core. Both assays are highly precise (CV's < 4%) and highly sensitive (PSA Total: analytical sensitivity < 0.02 ng/ml; PSA Free: < 0.01 ng/ml). The PSA
D, Groche, R, Trebo, I, Peters, P, Pfleiderer   +3 more
openaire   +1 more source

[Determination of free PSA in 85 consecutive cases with increased total PSA].

Schweizerische medizinische Wochenschrift, 1997
With a view to a more clearcut discrimination between benign prostatic hyperplasia (BPH) and prostate cancer (PCA), an additional measurement of the free PSA serum concentration and its ratio to total PSA (f-PSA/t-PSA) were determined in sera from 85 consecutive ambulatory patients with a total PSA concentration exceeding 4 ng/ml.
J P, Rothen, R, Vuillemin
openaire   +1 more source

1264: Percent Free PSA and PSA Density as Predictors of Progression-Free Survival

Journal of Urology, 2004
Kimberly A. Roehl, Jo Ann V. Antenor, Hui Zhu, Keegan L. Maxwell, William J. Catalona   +4 more
openaire   +1 more source