Results 151 to 160 of about 7,348 (250)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
HEADED RELATIVES, FREE RELATIVES, AND DETERMINER-HEADED FREE RELATIVES
ENGLISH LINGUISTICS, 2009 openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A compositional semantics for wh-ever free relatives
, 2019 This paper focuses on two puzzles posed by wh-ever free relatives (‘FRs’): wh-ever FRs (a) license ignorance inferences, and (b) display properties in common with questions. I propose to resolve these puzzles by unifying the analysis of wh-ever FRs with
Hirsch, Aron
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Pair-List vs. Single Pair Readings in Multiple Wh Free Relatives and Correlatives
Kansas Working Papers in Linguistics, 2008 Rudin, Catherine
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Unconventional relatives and antecedents in disguise: German clefts and free relative clauses
German clefts and free relatives are generally considered relative clauses. However, there is something special about them. Clefts resemble “regular” relative clauses but crucially differ from them in their semantics and functions, whereas free relatives
Sabrina Bertollo
core
, 2008 This thesis examines travel behavior and expenditure patterns of Chinese university students and the associated VFRs in New Zealand. It also investigates the effects of socio-demographics, travel-related, and psychographic variables on travel behavior ...
Ge, Liu
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