Results 91 to 100 of about 2,116,515 (307)
Application of a water-related environmental health epidemiological process : a guide for environmental health practitioners [PDF]
ThesisOne of the more suitable methodologies to follow to assess the impacts of environmental factors on the health of humans would be the epidemiological process.
Theron, Leana
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Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Published ArticleThis paper presents the application of a long-term streamflow forecasting model developed using artificial neural networks at a stream gauging station in the Awash River Basin, Ethiopia. The gauging station is located above the headworks
Babel, Mukand Singh +1 more
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Quality of drinking water sources in the Bloemfontein area of the Mangaung Metropolitan Municipality [PDF]
Thesis (M. Tech. (Environmental Health)) -- Central University of technology, Free State, 2013Introduction: Drinking water of poor quality can cause a variety of diseases and may even result in death.
Ratikane, Mosepeli
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Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Free-living protozoa in drinking water supplies: community composition and role as hosts for Legionella pneumophila Free-living protozoa, which feed on bacteria, play an important role in the communities of microorganisms and invertebrates in drinking
Valster, R.M.
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Evaluation of the management practices of small-scale dairy farmers in the North-Eastern Free State [PDF]
ThesisThe study evaluated the management practices of small-scale dairy farmers in the NorthEastern Free State. The sampling area focused on small-scale dairy farmers in the former self-governing territory of Qwaqwa, as well as parts of the Harrismith,
Masiteng, Takisi Janki
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Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A soil water model for two contrasting tillage systems
Techniques were developed to simulate the soil-plant environment as a semi-dynamic hydrologic system. Exponential expressions were found to give reasonable estimates of soil evaporation prior to corn plant emergence.
Lillard, James H., Shanholtz, Vernon O.
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

