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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gennady Gololob’s article, “Free Will: Pro and Con” is dedicated to the theme of the possibility and conditions for the manifestation of human free will.
Gennady GOLOLOB
doaj
Boltzmann sampling of irreducible context-free structures in linear time [PDF]
Andrea Sportiello
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
How I learned to stop worrying and love the alien hand syndrome [PDF]
Willusionists claim that science has proven free will to be an illusion. We propose a thought experiment that demonstrates how this view leads to an absurd conclusion: the term "free will" can no longer be applied differently to cases where agents ...
Levin Sergei, Farina Mirko
doaj +1 more source
iMiGUE: An Identity-free Video Dataset for Micro-Gesture Understanding and Emotion Analysis [PDF]
Xin Liu +5 more
openalex +1 more source
Jamesian Free Will, The Two-stage Model Of William James [PDF]
Research into two-stage models of “free will” – first “free” random generation of alternative possibilities, followed by “willed” adequately determined decisions consistent with character, values, and desires – suggests that William James was in 1884 the
Doyle, Bob
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
In order to find a convincing position in the “free will” debate, two sorts of determinism are distinguished. The merits of encompassing determinism, which is determinism as it is usually understood, and individual determinism, which focuses on the agent, are brought to the fore.
openaire +3 more sources
Structural, Chemical and Low Temperature Magnetic Properties of Lead Free 0.6NiFe2O4 - 0.4Na0.5Bi0.5TiO3 Magnetoelectric Composite [PDF]
G Jegadish Kumar +4 more
openalex +1 more source

