Results 91 to 100 of about 13,850,882 (338)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Gennady Gololob’s article, “Free Will: Pro and Con” is dedicated to the theme of the possibility and conditions for the manifestation of human free will.
Gennady GOLOLOB
doaj
4 × 20 Gbit/s mode division multiplexing over free space using vector modes and a q-plate mode (de)multiplexer [PDF]
Giovanni Milione +10 more
openalex +1 more source
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Dose-Response Effect of Elevated Plasma Free Fatty Acid on Insulin Signaling [PDF]
Renata Belfort +7 more
openalex +1 more source
Free will for everyone - with flaws [PDF]
Wegner's refutation of the notion of a conscious free will is addressed to a general reader. Despite a wide ranging and instructive survey and a conclusion acceptable to current psychological thinking, it is flawed by terminological confusions and lack ...
Mandler, G
core
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
In order to find a convincing position in the “free will” debate, two sorts of determinism are distinguished. The merits of encompassing determinism, which is determinism as it is usually understood, and individual determinism, which focuses on the agent, are brought to the fore.
openaire +3 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source

