Results 111 to 120 of about 17,880,075 (308)
Canadian Journal of Plastic Surgery, 2004 Surgeons believe in certain ideals. We believe we belong to a profession with intrinsic standards. These beliefs involve our duties to patients and our obligations to find the truth and patiently explain what we think in a way people can understand. We are translators and truth seekers and even though this sounds self-exalting, this is who we are. This
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Columbus Free Press subscription form
, 1990 Order form encouraging subscription to and financial support for the Columbus Free Press. It also announces that the newspaper will no longer be available for free, but can be obtained by subscription or for $1 per copy at Free Press newsboxes.
Columbus Free Press (Publisher)
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Columbus Free Press newsletter
, 1978 Newsletter sent to Columbus Free Press staff and volunteers, documenting the current financial status of the newspaper and relevant news. The Columbus Free Press began as a bi-weekly publication in Columbus, Ohio, in 1970.
Columbus Free Press (Publisher)
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Free Acres group photo at 25th anniversary, Summer 1935
, 1935 Group photograph of Free Acres inhabitants - taken during the summer of 1935 at the 25th anniversary celebration of the existence of Free Acres. Anniversary activities included sports, games, a play, and a slide show capturing the history of Free ...
Crawford, Will
core +1 more source