Results 91 to 100 of about 17,880,075 (308)
A Discretionary Case for Preservationism about Free Will
Humana.Mente: Journal of Philosophical Studies, 2022 How does the term ‘free will’ refer? This question seems to lie at the center of debates about whether the attitudes and practices that depend on our successful attributions of basic-desert-entailing moral responsibility ought to be preserved or ...
Kelly McCormick
doaj
Reflections on Sam Harris' "Free Will"
Rivista Internazionale di Filosofia e Psicologia, 2017 In his book Free Will Sam Harris tries to persuade us to abandon the morally pernicious idea of free will. The following contribution articulates and defends a more sophisticated model of free will that is not only consistent with neuroscience and ...
Daniel C. Dennett
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The Impact of Free Will Belief on Decision-Making and Life Satisfaction: A Comprehensive Analysis [PDF]
openThis thesis explores how belief in free will impacts decision-making and life satisfaction, integrating philosophical and psychological perspectives. It traces the concept's historical evolution, examines existentialist views, and analyzes individual
BORU, YASEMIN ADA
core
Free Will: A consensus gentium Argument [PDF]
Organon FThis argument for free will is a probabilistic one based upon two conjectures: first, that of consensus; namely, that a large majority of people believe that they and others have free will and second, that a priori proofs against the existence of free ...
William Hunt
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Free source as free thought: Architecting free standards
First Monday, 2000 As we build cyberspace, it is up to us, as individuals, not to promote illiteracy and proprietary standards that shut out those who fail to purchase computer programs from a specific vendor. It has become fashionable to blame others, such as Microsoft, for creating what is known as the "dark ages of computing". However, I suggest that we can and should
openaire +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
From free will to ultimate freedom [PDF]
Belgrade Philosophical AnnualThis essay begins with a discussion of free will, and finally offers a more robust theory of ultimate freedom. My basic claim is that ultimate freedom is compatible with complete scientific explanation of human choice in terms of preference.
Lehrer Keith
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