Results 61 to 70 of about 12,878,813 (328)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Free Will and Determinism: Political, Not Just Metaphysical [PDF]
, 2013 This paper is a short commentary on Veljko Dubljevic's "Autonomy in Neuroethics: Political and Not Metaphysical.
Johannsen, Kyle
core +1 more source
Entropy, 2017 Using insights from cybernetics and an information-based understanding of biological systems, a precise, scientifically inspired, definition of free-will is offered and the essential requirements for an agent to possess it in principle are set out. These
Keith Douglas Farnsworth
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Journal of Pure and Applied AlgebraConsider a diagram $\cdots \to F_3 \to F_2\to F_1$ of algebraic systems, where $F_n$ denotes the free object on $n$ generators and the connecting maps send the extra generator to some distinguished trivial element. We prove that (a) if the $F_i$ are free associative algebras over a fixed field then the limit in the category of graded algebras is again ...
Chirvasitu, Alexandru, Hong, Tao
openaire +2 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
The Metaphysics of Free Will: A Critique of Free Won’t as Double Prevention [PDF]
, 2015 The problem of free will is deeply linked with the causal relevance of mental events. The causal exclusion argument claims that, in order to be causally relevant, mental events must be identical to physical events.
Grasso, Matteo
core +3 more sources
Ideas y Valores, 2009 I have argued we are not free in the sense required for moral responsibility, while at the same time a conception of life without this type of free will would not be devastating to morality or to our sense of meaning in life, and in certain respects it ...
Derk Pereboom
doaj +2 more sources
Reflections on Sam Harris' "Free Will"
Rivista Internazionale di Filosofia e Psicologia, 2017 In his book Free Will Sam Harris tries to persuade us to abandon the morally pernicious idea of free will. The following contribution articulates and defends a more sophisticated model of free will that is not only consistent with neuroscience and ...
Daniel C. Dennett
doaj +1 more source
Sugar free, cancer free? [PDF]
Nutrition, 2012 The impact of diet on the prevention and treatment of cancer is an important area of investigation and the differential effects of caloric source—carbohydrates, protein, or fat—has been an area of particular interest. Carbohydrates provide energy but, unlike proteins and fat, also stimulate insulin signals that can be potent mitogens.
Andrea P. Myers, Lewis C. Cantley
openaire +3 more sources