Results 31 to 40 of about 128,671 (301)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Moreault F. Hannah Arendt: Eros for freedom of thought and love for political freedom = Hannah Arendt: Erôs de la liberté de penser et amour de la liberté politique / trans. from Fr. S. A. Zharinov

open access: yesОмский научный вестник: Серия "Общество. История. Современность"
The article examines the concept of love in the political theory of Hannah Arendt. The author focuses not on love-passion, which is a limited to the private sphere, but on political love, which Arendt presents in two forms associated with two forms of ...
S. A. Zharinov
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

STUDI KOMPARASI SAMINISME DENGAN JEAN PAUL SARTRE TENTANG KEBEBASAN (Tinjauan Filsafat Sosial)

open access: yesJurnal Filsafat, 2016
The comparative study between Saminism concept and Jean Paul Sartre thought of freedom are: 1) Human freedom, according to Sartre, is an absolute freedom.
Restu Trisnova
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

Comparative and Critical Study of the Concept of Freedom in the thought of Kant and Heidegger [PDF]

open access: yes, 2022
In a sense, freedom is one of the most important concepts in the history of philosophy, which plays a fundamental role in the thought of philosophers, but like many other concepts, it needs to be redefined in order to survive in new conditions.
Ali Aghaiepour   +2 more
core   +1 more source

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett   +5 more
wiley   +1 more source

Legal Aspects of the Financing of Religious Groups in Spain

open access: yesAge of Human Rights Journal, 2014
The purpose of this paper is to analyze the Spanish public polices in the financing of churches and religious organizations. According to this approach, and taking in account that the Spanish legal frame lack of a common regulation for all religious ...
Óscar Celador Angón
doaj  

An analysis of the Concept of Freedom and its Implications for Educational Theory and Practice in Egypt, 1805-2000 [PDF]

open access: yes, 2002
The current study attempts to analyse the learners' right to freedom in education in order to determine the nature and content of their education. This analysis will be in relation to the philosophy of education in Egypt to improve the efficiency of the ...
Shehata, Safaa Ahmed Mohamed
core  

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