Results 151 to 160 of about 115,173 (332)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Neural networks for illustration generation: towards the issue of adaptation practices

RUDN Journal of Studies in Literature and Journalism
Technologies are rapidly transforming the field of journalism. The phenomenon of convergence has long become the norm, and the term text in the media includes not only the verbal component, but also photos, videos, audio, graphics - that is, it ...
Olga S. Mukhina, Vladimir F. Oleshko
doaj   +1 more source

Southern Europe and its prospects in 6 Q&As [PDF]

, 2013
By Effie G. H. Pedaliu, Fellow at LSE IDEAS and James D.
Pedaliu, Effie G. H.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

ERP implementation for an administrative agency as a corporative frontend and an e-commerce smartphone app [PDF]

, 2017
This document contains all the descriptions, arguments and demonstrations of the researches, analysis, reasoning, designs and tasks performed to achieve the requirement to technologically evolve an managing agency in a way that, through a solution that ...
Font Escribano, Jaume, Reynoso Vasquez, Vilma Karina   +1 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Personality Traits of Freelancers Working Remotely

Вестник Московского университета. Серия 14: Психология
Background. Remote work has been gaining popularity for a long time. With the outbreak of the COVID-19 pandemic, remote work has become a necessity for many people.
Olga N. Rodina , Pavel N. Prudkov
doaj   +1 more source

Understanding Consumer’s Attitude on Fish Quality and Marketing Aspects in the Greek Market [PDF]

During the last decade the Greek fish market experienced significant changes affecting both the supply and the demand of fish. Fisheries have faced significant problems, such as overfishing and low productivity.
Batzios, Christos, Moutopoulos, D.K., Siardos, G.   +2 more
core   +1 more source

Higher education stimulating creative enterprise [PDF]

, 2011
This report summarises the research undertaken by the Business & Community School at the University for the Creative Arts (UCA), analysing ways that higher ediucation (HEIs) can support, and indeed stimulate, the creative economy.
Campbell, Frances, Ely, Philip
core   +1 more source