Results 61 to 70 of about 2,038,816 (256)

Freeze-thaw stability of oilseed rape oleosome emulsions [PDF]

open access: yes
This work investigated the stability of natural oleosome emulsions on freeze-thawing. Oleosomes were recovered from oilseed rape seeds following an aqueous extraction process using sodium bicarbonate (0.1 M).
Jakobi, R.   +15 more
core   +1 more source

Effect of freeze-thaw cycles on shear strength of unsaturated bentonite modified clay [PDF]

open access: yes, 2021
Freeze–thaw cycles is a seasonal process which occurs in many north regions of soils. Understanding the effects of freeze–thaw cycle on the physico-mechanical behaviours of soils is critical for construction stabilisation and reduce the freeze-thaw ...
Jing, Xin   +4 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

An adaptive prediction method for mechanical properties deterioration of sandstone under freeze–thaw cycles: a case study of Yungang Grottoes

open access: yesHeritage Science, 2021
Due to the location of the Yungang Grottoes, freeze–thaw cycles contribute significantly to the degradation of the mechanical properties of the sandstone.
Chenchen Liu   +5 more
doaj   +1 more source

Investigations of Dynamic Mechanical Performance of Rubber Concrete under Freeze-Thaw Cycle Damage

open access: yes, 2023
In order to study the effect of the freeze-thaw cycle on the integrity and dynamic mechanical performance of rubber concrete, the wave speed of rubber concrete specimens with 10% rubber volume was measured by a nonmetallic ultrasonic detector. The impact
Jingli Zhang
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Study on dynamic splitting and evolution mechanism of sandstone under freeze-thaw cycle

open access: yes矿业科学学报
This study attempts to investigate the dynamic tensile mechanical properties of sandstone under freeze-thaw cycle by using the split Hopkinson pressure bar (SHPB)test system to perform dynamic splitting tests on sandstone samples with freeze-thaw cycle 0,
YANG Guoliang   +4 more
doaj   +1 more source

Strength and Microscopic Damage Mechanism of Yellow Sandstone with Holes under Freezing and Thawing

open access: yesAdvances in Civil Engineering, 2020
In order to study the damage characteristics of the yellow sandstone containing pores under the freeze-thaw cycle, the uniaxial compression test of saturated water-stained yellow sandstones with different freeze-thaw cycles was carried out by rock servo ...
Huren Rong   +5 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Hero tags protect Fluc activity from freeze-thaw cycles.

open access: yes, 2022
(A) Schematic representation of the freeze-thaw cycles. (B) Freeze-thaw cycles of Fluc-WT. Fractions of remaining Fluc activities after the second cycle were calculated. Mean ± SD from 5 independent experiments are shown.
Eri Morimoto (12890115)   +2 more
core   +1 more source

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